Jaap Jan Zwaginga

professor in transfusion medicine, hematologist

Leiden University Medical Center

Netherlands

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About

Jaap Jan Zwaginga is a professor in transfusion medicine and a hematologist at Leiden University Medical Center in the Netherlands. His research focuses on immune modulation, hematologic conditions, and cell therapy, as reflected in his recent articles. Notable topics include dendritic cell functionality, immune profiles post-surgery, and the role of antibodies in various hematological disorders. His work also explores regulatory T cells, the immune signature in graft-versus-host disease, and the impact of hemoglobin modulation on patient outcomes.

Articles (14)

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2024

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2024

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2024

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2023

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2023

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2023

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2023

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2023

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2022

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2022

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2022

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2022

Collaborators (11)

Lukas Hawinkels

Associate professor-Head of research laboratory

Leiden University Medical Center

NETHERLANDS

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Roula Tsonaka

Assistant Professor

Leiden University Medical Center

NETHERLANDS

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Moises Huaman

Associate Professor

University of Cincinnati

UNITED STATES

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C. Ellen van der Schoot

Head of Department, Professor

Sanquin

NETHERLANDS

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Karoly Szuhai

Associate Professor

NETHERLANDS

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Rick Kapur

University of Amsterdam

NETHERLANDS

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Frederick Korley

University of Michigan

UNITED STATES

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Jerry Braun

Head of department Pulmonary Surgery

Amsterdam University Medical Centers

NETHERLANDS

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Tatjana Nikolic

Leiden University Medical Center

NETHERLANDS

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Robert J M Klautz

Leiden University Medical Center

NETHERLANDS

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Pieter Hiemstra

Professor of Respiratory cell Biology and Immunology

Leiden University Medical Center

NETHERLANDS

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Jaap Jan Zwaginga

Research Interests

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Articles (14)

Defining Human Regulatory T Cells beyond FOXP3: The Need to Combine Phenotype with Function

Antibodies against Platelet Glycoproteins in Clinically Suspected VITT Patients

Pulmonary and Systemic Immune Profiles Following Lung Volume Reduction Surgery and Allogeneic Mesenchymal Stromal Cell Treatment in Emphysema

Bridging the Gap Between Tolerogenic Dendritic Cells In Vitro and In Vivo: Analysis of Siglec Genes and Pathways Associated with Immune Modulation and Evasion

Local administration of mesenchymal stromal cells is safe and modulates the immune compartment in ulcerative proctitis

Coronavirus Disease 2019 Convalescent Plasma Outpatient Therapy to Prevent Outpatient Hospitalization: A Meta-Analysis of Individual Participant Data From 5 Randomized Trials

Leucocyte and platelet activation in cardiac surgery patients with and without lung injury: A prospective cohort study.

A unique immune signature in blood separates therapy-refractory from therapy-responsive acute graft-versus-host disease.

The interplay between GPIb/IX antibodies, platelet hepatic sequestration, and TPO levels in patients with chronic ITP.

Hemoglobin modulation affects physiology and patient reported outcomes in anemic and non-anemic subjects: An umbrella review.

Tolerogenic dendritic cells pulsed with islet antigen induce long-term reduction in T-cell autoreactivity in type 1 diabetes patients.

Remote Monitoring of Vital and Activity Parameters in Chronic Transfusion-Dependent Patients: A Feasibility Pilot Using Wearable Biosensors.

The haemostatic effect of deep-frozen platelets versus room temperature-stored platelets in the treatment of surgical bleeding: MAFOD-study protocol for a randomized controlled non-inferiority trial.

Outpatient convalescent plasma therapy for high-risk patients with early COVID-19: a randomized placebo-controlled trial.

Collaborators (11)

Lukas Hawinkels

Roula Tsonaka

Moises Huaman

C. Ellen van der Schoot

Karoly Szuhai

Rick Kapur

Frederick Korley

Jerry Braun

Tatjana Nikolic

Robert J M Klautz

Pieter Hiemstra

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