James C. Sacchettini

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Texas A&M University

United States

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Structure-based Discovery of Critical Vulnerabilities of Micobacteria

Open Date: 2012-09-01

Close Date: 2017-08-31

Articles (10)

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2024

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2023

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2022

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2022

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2021

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2021

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2021

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2021

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2021

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2020

Collaborators (10)

Arthur Laganowsky

Texas A&M University

UNITED STATES

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Sabine Ehrt

Professor

Weill Cornell Medical College

UNITED STATES

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Daniel Romo

Baylor University

UNITED STATES

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Arum Han

UNITED STATES

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Paul Gordon

Assistant Professor Educator

University of Cincinnati

UNITED STATES

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Lawrence Harris

NEW ZEALAND

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Song-I Han

Texas A&M University

UNITED STATES

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Jihyae Ann

Associate Research Professor

Seoul National University

SOUTH KOREA

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Gloria Conover

Instructional Assistant Professor

Texas A&M University

UNITED STATES

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Margaret Glasner

Associate Professor

Texas A&M University

UNITED STATES

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James C. Sacchettini

Research Interests

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Contact this professor

Recent Grants

Articles (10)

Inhibitors of the Thioesterase Activity of <i>Mycobacterium tuberculosis</i> Pks13 Discovered Using DNA-Encoded Chemical Library Screening

DAIKON: A Data Acquisition, Integration, and Knowledge Capture Web Application for Target-Based Drug Discovery

A portable brightfield and fluorescence microscope toward automated malarial parasitemia quantification in thin blood smears

Structural anatomy of Protein Kinase C C1 domain interactions with diacylglycerol and other agonists

Metabolic bifunctionality of Rv0812 couples folate and peptidoglycan biosynthesis in Mycobacterium tuberculosis

Mechanism-Based Inactivation of <i>Mycobacterium tuberculosis</i> Isocitrate Lyase 1 by (2<i>R</i>,3<i>S</i>)-2-Hydroxy-3-(nitromethyl)succinic acid.

Development of single-cell-level microfluidic technology for long-term growth visualization of living cultures of Mycobacterium smegmatis

Second-Shell Amino Acid R266 Helps Determine N-Succinylamino Acid Racemase Reaction Specificity in Promiscuous N-Succinylamino Acid Racemase/o-Succinylbenzoate Synthase Enzymes

Covalent Inactivation of Mycobacterium tuberculosis Isocitrate Lyase by cis-2,3-Epoxy-Succinic Acid

Improvement of the novel inhibitor for Mycobacterium enoyl-acyl carrier protein reductase (InhA): a structure–activity relationship study of KES4 assisted by in silico structure-based drug screening

Collaborators (10)

Arthur Laganowsky

Sabine Ehrt

Daniel Romo

Arum Han

Paul Gordon

Lawrence Harris

Song-I Han

Jihyae Ann

Gloria Conover

Margaret Glasner

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