Jihyae Ann

Associate Research Professor

Seoul National University

South Korea

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Jihyae Ann is an Associate Research Professor at Seoul National University, South Korea. Her research focuses on analgesics, receptor antagonists, and cancer therapeutics, with recent articles highlighting innovative approaches in pain management and the development of agents for neurological and oncological disorders. Her work includes the discovery of novel compounds targeting various receptors and their potential applications in treating diseases such as Alzheimer's and breast cancer.

Articles (11)

Year:

2025

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2023

Year:

2022

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2022

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2021

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2021

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2021

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2021

Year:

2021

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2021

Year:

2021

Collaborators (7)

James C. Sacchettini

Texas A&M University

UNITED STATES

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Bernhard Wünsch

Professor

Westfälische Wilhelms-Universität Münster

GERMANY

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Jiyoun Lee

Professor

Sungshin Women's University

SOUTH KOREA

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Umberto Laforenza

University of Pavia

ITALY

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YOONJI LEE

Associate Professor

Chung-Ang University

SOUTH KOREA

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Marco Peviani

Assitant Professor (RTDB)

University of Pavia

ITALY

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Simona Collina

University of Pavia

ITALY

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Jihyae Ann

Research Interests

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Articles (11)

Discovery of a Novel Multitarget Analgesic Through an In Vivo-Guided Approach

Discovery of RC-752, a Novel Sigma-1 Receptor Antagonist with Antinociceptive Activity: A Promising Tool for Fighting Neuropathic Pain

Structural anatomy of Protein Kinase C C1 domain interactions with diacylglycerol and other agonists

Discovery of Novel Dual Adenosine A2A and A1 Receptor Antagonists with 1H-Pyrazolo[3,4-d]pyrimidin-6-amine Core Scaffold as Anti-Parkinson’s Disease Agents

Discovery of Benzopyridone-Based Transient Receptor Potential Vanilloid 1 Agonists and Antagonists and the Structural Elucidation of Their Activity Shift

The C-terminal HSP90 inhibitor NCT-58 kills trastuzumab-resistant breast cancer stem-like cells

Discovery of 5-(N-hydroxycarbamimidoyl) benzofuran derivatives as novel indoleamine 2,3-dioxygenase 1 (IDO1) inhibitors

2-(Halogenated Phenyl) acetamides and propanamides as potent TRPV1 antagonists

Discovery of a simplified deguelin analog as an HSP90 C-terminal inhibitor for HER2-positive breast cancer

Discovery of highly potent human glutaminyl cyclase (QC) inhibitors as anti-Alzheimer's agents by the combination of pharmacophore-based and structure-based design

The KDM5 Inhibitor KDM5-C70 Induces Astrocyte Differentiation in Rat Neural Stem Cells

Collaborators (7)

James C. Sacchettini

Bernhard Wünsch

Jiyoun Lee

Umberto Laforenza

YOONJI LEE

Marco Peviani

Simona Collina

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