James McCormick

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Associate Professor

Oregon Health & Science University

United States

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Recent Grants

Grant: Open

Renal mechanisms of hypomagnesemia: leveraging new technologies and therapies

Open Date: 2023-04-01

Close Date: 2028-03-30

Grant: Close

Regulation of renal ion transport by the CUL3-WNK-SPAK pathway

Open Date: 2019-06-14

Close Date: 2020-05-31

Grant: Close

Regulation of renal ion transport by the CUL3-WNK-SPAK pathway

Open Date: 2014-04-01

Close Date: 2023-12-31

Grant: Close

Regulation of renal sodium transport by a SPAK/OSR1 kinase network

Open Date: 2012-01-01

Close Date: 2013-12-31

Grant: Close

Analysis of distal conboluted tubule function in vivo

Open Date: 2008-04-01

Close Date: 2013-06-28

Articles (16)

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2024

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2021

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2021

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2020

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2020

Collaborators (8)

Robert A. Fenton

Aarhus University

DENMARK

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Michael P. Hutchens

UNITED STATES

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Motoko Yanagita

Professor

Kyoto Prefectural University of Medicine

JAPAN

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James Stockand

Professor

University of Texas Health Science Center at San Antonio

UNITED STATES

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Kiyoshi Mori

Professor

Shizuoka Graduate University of Public Health

JAPAN

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Sebastian Bachmann

Charité - Universitätsmedizin Berlin

GERMANY

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David H. Ellison

Oregon Health & Science University

UNITED STATES

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Turgay Saritas

University Hospital RWTH Aachen

GERMANY

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James McCormick

Research Interests

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Recent Grants

Articles (16)

Cullin3/WNK/SPAK Signaling: Impact on NaCl Cotransporter Activity in Blood Pressure Regulation

Renal upregulation of NCC counteracts empagliflozin-mediated NHE3 inhibition in normotensive but not in hypertensive male rat

Regulation of the water channel aquaporin-2 by cullin E3 ubiquitin ligases

Enriched Single-Nucleus RNA-Sequencing Reveals Unique Attributes of Distal Convoluted Tubule Cells

Dysregulation of the WNK4-SPAK/OSR1 pathway has a minor effect on baseline NKCC2 phosphorylation

Role of Angiotensin II Type 1a Receptor (AT1aR) of Renal Tubules in Regulating Inwardly Rectifying Potassium Channels 4.2 (Kir4.2), Kir4.1, and Epithelial Na + Channel (ENaC)

mTORC2, a Novel “Twist” on the Epithelial Sodium Channel (ENaC)

Cullin 3 and Blood Pressure Regulation: Insights From Familial Hyperkalemic Hypertension

Cullin 3 mutant causing familial hyperkalemic hypertension lacks normal activity in the kidney

Chronic activation of vasopressin-2 receptors induces hypertension in Liddle mice by promoting Na+ and water retention

Cisplatin-Induced Kidney Injury: Delivering the Goods

Cilastatin Ameliorates Rhabdomyolysis-induced AKI in Mice

Molecular Mechanisms of Renal Magnesium Reabsorption

Roles of WNK4 and SPAK in K+-mediated dephosphorylation of the NaCl cotransporter

NaCl cotransporter activity and Mg2+ handling by the distal convoluted tubule

The acute kidney injury to chronic kidney disease transition in a mouse model of acute cardiorenal syndrome emphasizes the role of inflammation

Collaborators (8)

Robert A. Fenton

Michael P. Hutchens

Motoko Yanagita

James Stockand

Kiyoshi Mori

Sebastian Bachmann

David H. Ellison

Turgay Saritas

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