James Stockand
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Recent Grants
Grant: Close
Regulation of ENaC by Casein Kinase 2
Open Date: 2018-09-05
Close Date: 2022-08-31
Grant: Close
Purinergic regulation of ENaC in the distal nephron
Open Date: 2018-05-01
Close Date: 2022-03-31
Grant: Close
Purinergic regulation of ENaC
Open Date: 2017-01-01
Close Date: 2018-12-31
Grant: Close
Defining the Contribution of ENaC to ADH-mediated Water and Sodium Excretion
Open Date: 2016-07-25
Close Date: 2020-03-31
Grant: Close
Cellular Mechanisms of Chemotherapy-Induced Peripheral Neuropathy
Open Date: 2015-04-01
Close Date: 2017-09-30
Articles (2)
Year:
2022
Activity of the epithelial Na + channel (ENaC) in the distal nephron fine-tunes renal Na + excretion. Angiotensin II (ANG II) has been reported to enhance ENaC activity. Emerging evidence suggests that NADPH oxidase (NOX) signaling plays an important role in the stimulation of ENaC by ANG II in principal cells. The present findings indicate that NOX activator 1/NOX1 signaling mediates ANG II stimulation of ENaC in renal principal cells.
Year:
2022
Collaborators (2)
Tarek Mohamed Abd El-Aziz
University of Texas Health Science Center at San Antonio
James McCormick
Associate Professor
Oregon Health & Science University
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