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James Wilmott

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Associate Professor

The University of Sydney Library

Australia

Research Interests

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About

Dr. James Wilmott is an Associate Professor at The University of Sydney Library, Australia. His research focuses on precision medicine in cancer, with recent publications exploring genomic tests for malignancies, tissue-based profiling techniques, and insights into melanoma subtypes. His work includes significant contributions to understanding the response to checkpoint inhibitors and identifying biomarkers associated with treatment outcomes in melanoma.

Recent Grants

Grant: Open

Personalised Immunotherapy Program – Precision immunotherapies for multiple solid tumours using a biomarker driven adaptive enrichment clinical trials platform

Open Date: 2022-01-01

Close Date: 2026-12-01

Grant: Close

Rational clinical trial design and treatment selection for advanced cancer patients.

Open Date: 2019-08-29

Close Date:

Grant: Close

Effective therapies for patients with high risk in-transit disease

Open Date: 2019-01-01

Close Date: 2023-07-01

Grant: Close

Melanotransferrin: A â Missing Linkâ and a Novel Pharmacological Target for Treatment

Open Date: 2018-01-01

Close Date: 2020-12-31

Grant: Close

The mutational landscape of melanoma in adolescents and young adults

Open Date: 2016-01-01

Close Date: 2019-01-01

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Collaborators (36)

Kristijan Skok

Medical University of Graz

AUSTRIA

James Wilmott

Research Interests

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About

Recent Grants

Articles (30)

Molecular Profiling and Matched Targeted Therapy for Patients With Advanced Melanoma: Results From Part 1 of the MatchMEL Study

Deep Learning Framework for Classifying Whole-Slide Multiplex Immunofluorescence Images to Predict Immunotherapy Response in Melanoma Patients

Image quality assessment of imputation-induced biomarker distortions in multiplex immunofluorescence

A randomised pilot trial of perioperative propranolol combined with celecoxib versus standard of care in stage III melanoma: The ProCel study protocol

Abstract 2883: Divergent gut microbial communities are linked to differences in baseline immune profiles, tumor features and ICI outcomes in melanoma

NeoIRENIE: A phase 2 randomized trial of intensified neoadjuvant therapy for melanoma patients with multi-omic biomarker or clinically predicted poor response to standard immune checkpoint inhibitor (ICI) therapy.

A-241 Genomic Profiling to Predict Immunotherapy Response in Merkel Cell Carcinoma

Neoadjuvant triplet immune checkpoint blockade in newly diagnosed glioblastoma

Pathologist-Read vs AI-Driven Assessment of Tumor-Infiltrating Lymphocytes in Melanoma.

Discovery and Validation of an Ancillary Genomic Test of Malignancy for Primary Melanocytic Tumors

Longitudinal Analysis Reveals Dynamic Changes in Histopathologic Features in Responders to Neoadjuvant Treatment in a Stage III BRAF-Mutant Melanoma Cohort

Do BRAF-targeted therapies have a role in the era of immunotherapy?

Stain imputation in multiplex immunofluorescence imaging (SIMIF) based on random channel-wise masking

Spatial and multiomics analysis reveals immune interactions as key drivers of immunotherapy outcomes in melanoma patients with in-transit metastases

Factors Associated With Implementation of Biomarker Testing and Strategies to Improve Its Clinical Uptake in Cancer Care: Systematic Review Using Theoretical Domains Framework

117MO Clinical and multi-omics predictive model of resistance to neoadjuvant anti-PD1 (PD1) in melanoma

Multiomic analysis of cutaneous squamous cell carcinoma (cSCC) and association with response to anti-PD1 therapy (PD1).

Rational use of adjuvant anti-PD-1: Multi-omics model of recurrence in stage III melanoma.

Abstract 172: Spatial profiling of stage III melanoma microenvironment reveals tertiary lymphoid structures as markers of long-term outcomes

Tissue-Based Profiling Techniques to Achieve Precision Medicine in Cancer: Opportunities and Challenges in Melanoma

Spatial mapping reveals granuloma diversity and histopathological superstructure in human tuberculosis

Clinical Features Associated with Outcomes and Biomarker Analysis of Dabrafenib plus Trametinib Treatment in Patients with BRAF-Mutant Melanoma Brain Metastases

Comparative Genomics Provides Etiologic and Biological Insight into Melanoma Subtypes

Multiomic profiling of checkpoint inhibitor-treated melanoma: Identifying predictors of response and resistance, and markers of biological discordance

G9a Inhibition Enhances Checkpoint Inhibitor Blockade Response in Melanoma

γδ T Cells in Merkel Cell Carcinomas Have a Proinflammatory Profile Prognostic of Patient Survival

Publisher Correction: Molecular analysis of primary melanoma T cells identifies patients at risk for metastatic recurrence

Molecular analysis of primary melanoma T cells identifies patients at risk for metastatic recurrence

Close proximity of immune and tumor cells underlies response to anti-PD-1 based therapies in metastatic melanoma patients

Integration of Digital Pathologic and Transcriptomic Analyses Connects Tumor-Infiltrating Lymphocyte Spatial Density With Clinical Response to BRAF Inhibitors

Collaborators (36)

Kristijan Skok

Shlomo Berkovsky

Russell Diefenbach

Ghamdan Al-Eryani

Graham Mann

Irene Gullo

Nigel Gordon Maher

Dannel Yeo

Sidong Liu

Serigne N. Lô

Beatrice Dyring-Andersen

Nikos Tsiknakis

Joel Ernst

Ellis Patrick

Alexander Christopher Jonathan van Akkooi

Anne E Cust

Balazs Acs

Jordan Conway

Antonia Pritchard

Wiebke Solass

Chenhao Zhou

Andrea Boutros

Elena Shklovskaya

Katia Nones

Francesco Casciello

Nir Pillar

Rebecca Simpson

Guy Lyons

carl feng

Richard A. Scolyer

Helen Rizos

Tobias Sinnberg

Francesca Maria Bosisio

John E. J. Rasko

Bart Neyns

Ines Pires da Silva

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