Jan Parys

Full Professor and Head of the Lab. Molecular and Cellular Signalling

KU Leuven

Belgium

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Articles (10)

Year:

2023

Year:

2023

Year:

2022

Year:

2022

Year:

2022

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2022

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2022

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2022

Year:

2021

Year:

2021

Collaborators (10)

BRUNO QUESNEL

Professor, Head of the Leukemia and MDS department

Centre Hospitalier Régional Universitaire de Lille

FRANCE

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Axel Methner

University Medical Center of the Johannes Gutenberg University Mainz

GERMANY

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Ingrid Fliniaux

Université de Lille

FRANCE

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Nicolas Rosa

University of Geneva

SWITZERLAND

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David Bernard

FRANCE

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Dimitra Gkika

Associate Professor in Physiology

Université de Lille

FRANCE

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Dhanendra Tomar

Assistant Professor

Wake Forest Baptist Medical Center

UNITED STATES

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Yasmine TOUIL

FRANCE

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Fabien Van Coppenolle

Professor

Université Claude Bernard Lyon 1

FRANCE

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jerome kluza

Professor

Université de Lille

FRANCE

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Jan Parys

Research Interests

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Articles (10)

Modalities of cell death, survival and adaptation: The role of the Ca2+-signaling toolkit

The ER-mitochondria interface, where Ca2+ and cell death meet

TMBIM5 loss of function alters mitochondrial matrix ion homeostasis and causes a skeletal myopathy

TRPC3 shapes the ER-mitochondria Ca<sup>2+</sup> transfer characterizing tumour-promoting senescence.

Sec61 complex/translocon: The role of an atypical ER Ca<sup>2+</sup>-leak channel in health and disease.

Modulation of Ca<sup>2+</sup> signaling by antiapoptotic Bcl-2 versus Bcl-xL: From molecular mechanisms to relevance for cancer cell survival.

Rhomboid pseudoproteases: An Achilles heel's for BCL-2/IP3R-dependent resistance to ER stress-induced cell death

A non-canonical role for pyruvate kinase M2 as a functional modulator of Ca<sup>2+</sup> signalling through IP<sub>3</sub> receptors.

Preface to the Special Issue of the European Calcium Society in honor of Professor Sir Michael J. Berridge.

Bcl-xL acts as an inhibitor of IP<sub>3</sub>R channels, thereby antagonizing Ca<sup>2+</sup>-driven apoptosis.

Collaborators (10)

BRUNO QUESNEL

Axel Methner

Ingrid Fliniaux

Nicolas Rosa

David Bernard

Dimitra Gkika

Dhanendra Tomar

Yasmine TOUIL

Fabien Van Coppenolle

jerome kluza

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