Dhanendra Tomar

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Assistant Professor

Wake Forest Baptist Medical Center

United States

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About

Dhanendra Tomar is an Assistant Professor at Wake Forest Baptist Health in the United States. His research primarily focuses on mitochondrial function in relation to neurodegenerative diseases and cardiovascular health, as evidenced by his recent articles on Alzheimer's disease, Parkinson's disease, and diabetic ischemic heart disease. He is particularly interested in the mechanisms of calcium signaling and mitochondrial structure in various pathological conditions.

Recent Grants

Grant: Close

Impact of mitochondrial structure on cellular homeostasis and hepatic injury

Open Date: 2022-05-16

Close Date: 2025-04-30

Grant: Close

Impact of mitochondrial structure on cellular homeostasis and hepatic injury

Open Date: 2020-03-01

Close Date: 2022-02-28

Grant: Close

Impact of mitochondrial structure on cellular homeostasis and cardiac ischemia-reperfusion (IR)-injury

Open Date: 2019-04-01

Close Date: 2022-06-30

Grant: Close

Mitochondrial Calcium Uniporter Mediated Regulation of Hepatic Lipid Metabolism and its Therapeutic Implications

Open Date: 2017-07-01

Close Date: 2019-06-30

Grant: Close

To study the role of TRIM4/RNF87 in mitochondrial metabolism and physiology

Open Date: 2013-12-01

Close Date: 2014-06-01

Articles (22)

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2020

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2020

Collaborators (18)

Pooja Jadiya

Assistant Professor

Wake Forest Baptist Medical Center

UNITED STATES

Dhanendra Tomar

Research Interests

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About

Recent Grants

Articles (22)

Mitochondrial connection to Alzheimer’s disease and heart failure

TRIM71 bound hsa-miR-30b-5p restores mitochondrial function in a cellular model of Parkinson's disease.

3D Mitochondrial Structure in Aging Human Skeletal Muscle: Insights Into MFN-2-Mediated Changes.

TMEM65 regulates and is required for NCLX-dependent mitochondrial calcium efflux.

Enhancing VEGF therapy in T2D wounds with PLCγ2 epigenetic targeting

Integrated single-cell RNA-seq analysis reveals mitochondrial calcium signaling as a modulator of endothelial-to- mesenchymal transition

Role of mitochondrial ribosomal protein L7/L12 (MRPL12) in diabetic ischemic heart disease.

MICU1's calcium sensing beyond mitochondrial calcium uptake.

Calcium signaling in mitochondrial intermembrane space

ERMCS Ca2+ transmission fuels cell division

MICU1 regulates mitochondrial cristae structure and function independently of the mitochondrial Ca 2+ uniporter channel

Editorial: Oxidative stress link associated with mitochondrial bioenergetics: relevance in cell aging and age-related pathologies.

Post-translational modifications and protein quality control of mitochondrial channels and transporters.

Suppression of Ca2+ signaling enhances melanoma progression

TMBIM5 loss of function alters mitochondrial matrix ion homeostasis and causes a skeletal myopathy

MICU1-dependent mitochondrial calcium uptake regulates lung alveolar type 2 cell plasticity and lung regeneration

SARS-CoV-2 infection enhances mitochondrial PTP complex activity to perturb cardiac energetics.

Molecular Signature of HFpEF: Systems Biology in a Cardiac-Centric Large Animal Model.

Human neurotropic polyomavirus, JC virus, agnoprotein targets mitochondrion and modulates its functions

Yeast homologs of human MCUR1 regulate mitochondrial proline metabolism

SARS-CoV-2, ACE2, and Hydroxychloroquine: Cardiovascular Complications, Therapeutics, and Clinical Readouts in the Current Settings

Mitochondrial Protein Quality Control Mechanisms

Collaborators (18)

Pooja Jadiya

Axel Methner

Vernat Exil

Kumaraswamy naidu Chitrala

David Dombrowicz

Gyorgy Hajnoczky

Brij B. Singh

MARTA MURGIA

Tarek Mohamed Abd El-Aziz

Henry Cohen

Valerie Gouyer

Yonglun Luo

Jan Parys

John W. Elrod

Anna Rita Cantelmo

Andrew Gibb

Rafal Kaminski

Anita Quintana

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