Javier Sánchez Romero

Objective To analyze the influence of the resting interval after removal of a double‐balloon for cervical ripening and oxytocin administration on the time to onset of active labor in singleton pregnancies. Methods A retrospective cohort study of women who required a cervical ripening with double‐balloon was conducted between January 2019 and December 2022. We collected data for cervical ripening balloon insertion and removal, oxytocin administration, suspicious or pathological cardiotocographic trace, mode of delivery, maternal and neonatal complications, neonatal outcomes. Proportional hazards model comparing resting interval between double‐balloon cervical ripening removal and oxytocin administration. Results A total of 403 singleton pregnancies were recruited and 213 pregnant women experienced a rest of 12 h between cervical balloon removal and oxytocin administration (resting group). Oxytocin was administered immediately after balloon removal in 190 women (non‐resting group). Median insertion‐to‐active labor interval and insertion‐to‐delivery interval were significantly shorter in the non‐resting group: 18.5 versus 24.0 h, HR 2.59 (CI 95%: 1.97–3.41) and 24.0 versus 29.0 h, HR 2.38 (CI 95%: 1.85–3.05) respectively. Bishop score change and mode of delivery between were similar in both groups. No differences in maternal nor neonatal complications between both groups were found. Conclusions Oxytocin administration immediately after removal of a double‐balloon for cervical ripening compared with 12 h delayed interval resulted in a shortened time from insertion to active labor onset and to delivery interval without increasing maternal or neonatal adverse outcomes.