Jean-Philippe Gagne

Professionnel de recherche

Université Laval

Canada

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Jean-Philippe Gagne is a research professional at Université Laval in Canada. His research focuses on the molecular mechanisms of DNA repair, alternative splicing, and cellular responses to bioenergetic challenges. Recent articles highlight his work on the interaction between PARP1/2 and DNA-binding proteins, as well as the role of the prefoldin complex in protein stability.

Articles (5)

Year:

2025

Year:

2025

Year:

2024

Year:

2021

Year:

2020

Collaborators (5)

Valina Dawson

Professor

Johns Hopkins University School of Medicine

UNITED STATES

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Guy Poirier

Professor

CANADA

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Peter King

The University of Alabama

UNITED STATES

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François-Michel Boisvert

CANADA

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Guy Sauvageau

Affiliated professor

Université de Montréal

CANADA

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Jean-Philippe Gagne

Research Interests

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Articles (5)

CHD6 has poly(ADP-ribose)- and DNA-binding domains and regulates PARP1/2-trapping inhibitor sensitivity via abasic site repair

Proteomic study identifies Aurora-A–mediated regulation of alternative splicing through multiple splicing factors

Poly(ADP‐ribose) mediates bioenergetic defects and redox imbalance in neurons following oxygen and glucose deprivation

Zinc finger protein E4F1 cooperates with PARP-1 and BRG1 to promote DNA double-strand break repair.

The prefoldin complex stabilizes the von Hippel-Lindau protein against aggregation and degradation.

Collaborators (5)

Valina Dawson

Guy Poirier

Peter King

François-Michel Boisvert

Guy Sauvageau

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