Jelmer Hoeksma

Hubrecht Institute for Developmental Biology and Stem Cell Research

Netherlands

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Articles (9)

Year:

2024

Antibiotics are becoming less effective against bacterial infections due to the evolution of resistance among bacteria. Pseudomonas aeruginosa is a Gram-negative pathogen that causes major health care concerns and is difficult to treat due to its high intrinsic resistance to antimicrobial agents. Therefore, new targets are needed, and an interesting approach is to target quorum sensing (QS).

Year:

2023

Year:

2023

Year:

2022

Year:

2022

Year:

2022

Year:

2021

Year:

2021

Year:

2020

Collaborators (4)

Jeroen den Hertog

NETHERLANDS

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Giada Cattani

Università degli Studi di Roma La Sapienza

ITALY

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Lorenzo Stella

Associate Professor of Physical Chemistry

University of Rome Tor Vergata

ITALY

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dr. Gisela van der Velden

Assistant professor Educational Innovation

NETHERLANDS

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Jelmer Hoeksma

Research Interests

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Articles (9)

Harzianic acid exerts antimicrobial activity against Gram-positive bacteria and targets the cell membrane

Paecilomycone Inhibits Quorum Sensing in Gram-Negative Bacteria

Loss of Shp1 impairs myeloid cell function and causes lethal inflammation in zebrafish larvae

Gregatins, a Group of Related Fungal Secondary Metabolites, Inhibit Aspects of Quorum Sensing in Gram-Negative Bacteria

Classification of antimicrobial mechanism of action using dynamic bacterial morphology imaging

Evolution-Informed Discovery of the Naphthalenone Biosynthetic Pathway in Fungi

Targeting Oncogenic Src Homology 2 Domain-Containing Phosphatase 2 (SHP2) by Inhibiting Its Protein–Protein Interactions

Berkchaetoazaphilone B has antimicrobial activity and affects energy metabolism

Cercosporamide inhibits bone morphogenetic protein receptor type I kinase activity in zebrafish

Collaborators (4)

Jeroen den Hertog

Giada Cattani

Lorenzo Stella

dr. Gisela van der Velden

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