Jens Markus Borghardt

Director - Global Head of Preclinical PKPD Modelling & Digital and Data Sciences

Boehringer Ingelheim Pharmaceuticals Inc

Germany

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Jens Markus Borghardt is the Director and Global Head of Preclinical PKPD Modelling & Digital and Data Sciences at Boehringer Ingelheim Pharma GmbH & Co. KG in Germany. His research focuses on pharmacokinetics and pharmacodynamics, with recent articles exploring machine learning applications for predicting pharmacokinetics, as well as holistic approaches to compound quality scores. He emphasizes the integration of diverse datasets and the analysis of established antibiotics for inhalation based on pharmacokinetic perspectives.

Articles (10)

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2025

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2024

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2024

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2023

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2023

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2022

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2022

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2022

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2022

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2020

Collaborators (3)

Sebastian G. Wicha

Junior Professor of Clinical Pharmacy

Universität Hamburg

GERMANY

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Niklas Hartung

University of Potsdam

GERMANY

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Bernd Meibohm

UNITED STATES

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Jens Markus Borghardt

Research Interests

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Articles (10)

Predicting Pharmacokinetics in Rats Using Machine Learning: A Comparative Study Between Empirical, Compartmental, and PBPK‐Based Approaches

Beyond CL and VSS: A comprehensive approach to human pharmacokinetic predictions

Multi‐Task ADME/PK prediction at industrial scale: leveraging large and diverse experimental datasets**

Barriers to global pharmacometrics: educational challenges and opportunities across the globe

Towards holistic Compound Quality Scores: Extending ligand efficiency indices with compound pharmacokinetic characteristics

Inferring pulmonary exposure based on clinical PK data: accuracy and precision of model-based deconvolution methods

Understanding the suitability of established antibiotics for oral inhalation from a pharmacokinetic perspective: an integrated model-based investigation based on rifampicin, ciprofloxacin and tigecycline in vivo data

Evaluating prediction methods for glomerular filtration to optimise drug doses in obese and nonobese patients

An integrative pharmacokinetic-cardiovascular physiology modelling approach based on in vivo dog studies including five reference compounds

A mechanistic framework for a priori pharmacokinetic predictions of orally inhaled drugs

Collaborators (3)

Sebastian G. Wicha

Niklas Hartung

Bernd Meibohm

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