Sebastian G. Wicha

Junior Professor of Clinical Pharmacy

Universität Hamburg

Germany

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Dr. Sebastian G. Wicha is a Junior Professor of Clinical Pharmacy at the University of Hamburg, Germany. His research primarily focuses on therapeutic drug monitoring, pharmacokinetics, and precision dosing in clinical settings. Recent publications include studies on infliximab monitoring, chimeric antigen receptor T-cell therapy, and pharmacokinetic evaluations of various antibiotic regimens. Dr. Wicha is committed to advancing clinical practices to improve patient outcomes in pharmacy.

Articles (20)

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2024

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2022

Collaborators (8)

Pieter De Cock

Assistant professor

Ghent University

BELGIUM

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Valentin al Jalali

Medical University of Vienna

AUSTRIA

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Felix Bergmann

Medical University of Vienna

AUSTRIA

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Dominik Jarczak

University Medical Center Hamburg-Eppendorf

GERMANY

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Jean-Winoc DECOUSSER

Université Paris-Est Créteil Val de Marne

FRANCE

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Debby Thomas

Katholieke Universiteit Leuven

BELGIUM

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Jens Markus Borghardt

Director - Global Head of Preclinical PKPD Modelling & Digital and Data Sciences

Boehringer Ingelheim Pharmaceuticals Inc

GERMANY

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Ron Keizer

Chief Scientific Officer

UNITED STATES

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Sebastian G. Wicha

Research Interests

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About

Articles (20)

Pharmacokinetic/pharmacodynamic analysis of ceftazidime/avibactam and fosfomycin combinations in an in vitro hollow fiber infection model against multidrug-resistant Escherichia coli

Effect of albumin substitution on pharmacokinetics of piperacillin/tazobactam in patients with severe burn injury admitted to the ICU

Best Practice for Therapeutic Drug Monitoring of Infliximab: Position Statement from the International Association of Therapeutic Drug Monitoring and Clinical Toxicology

Chimeric antigen receptor T-cell therapy and fludarabine: precision dosing imperatives

Impact of Key Components of Intensified Ceftaroline Dosing on Pharmacokinetic/Pharmacodynamic Target Attainment

Pharmacokinetic/pharmacodynamic evaluation of tigecycline dosing in a hollow fiber infection model against clinical bla-KPC producing Klebsiella Pneumoniae isolates

Pharmacokinetics and pharmacological target attainment of standard temocillin dosing in non-critically ill patients with complicated urinary tract infections

Study protocol for ADAPT-TDM: A beta-lactam antibiotic Dose AdaPtation feasibility randomised controlled Trial using Therapeutic Drug Monitoring

Towards a better detection of patients at-risk of linezolid toxicity in clinical practice: a prospective study in three Belgian hospital centers

Towards clinically relevant dose ratios for Cabamiquine and Pyronaridine combination using P. falciparum field isolate data

Model-informed precision dosing of vancomycin via continuous infusion: a clinical fit-for-purpose evaluation of published PK models

A Machine Learning Approach to Predict Interdose Vancomycin Exposure

A dosing nomograph for cerebrospinal fluid penetration of meropenem applied by continuous infusion in patients with nosocomial ventriculitis

Ciprofloxacin in Patients Undergoing Extracorporeal Membrane Oxygenation (ECMO): A Population Pharmacokinetic Study

Inferring pulmonary exposure based on clinical PK data: accuracy and precision of model-based deconvolution methods

Liver function, quantified by the LiMAx test, as a predictor for the clinical outcome of critically ill patients treated with linezolid

Multi-model averaging improves the performance of model-guided infliximab dosing in patients with inflammatory bowel diseases

Optimized sampling to estimate vancomycin drug exposure: Comparison of pharmacometric and equation-based approaches in a simulation-estimation study

Pharmacokinetics and Pharmacodynamics of Tedizolid

Population Pharmacokinetics of Busulfan and Its Metabolite Sulfolane in Patients with Myelofibrosis Undergoing Hematopoietic Stem Cell Transplantation

Collaborators (8)

Pieter De Cock

Valentin al Jalali

Felix Bergmann

Dominik Jarczak

Jean-Winoc DECOUSSER

Debby Thomas

Jens Markus Borghardt

Ron Keizer

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