Jermaine Jenkins

Research Assistant Prof.

University of Rochester

United States

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About

Jermaine Jenkins is a Research Assistant Professor at the University of Rochester, USA. His research primarily focuses on RNA-mediated gene regulation, metabolite binding, and the structural analysis of riboswitches. Recent publications explore topics such as cyclic peptides and their application against SARS-CoV-2, as well as the implications of cancer-associated mutations on RNA splicing and interactions.

Articles (8)

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2024

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2024

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2023

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2022

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2021

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2020

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2020

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2020

Collaborators (2)

Joseph Wedekind

Professor

University of Rochester School of Medicine and Dentistry

UNITED STATES

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Zackary Falls

Assistant Professor

University at Buffalo - Downtown Campus

UNITED STATES

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Jermaine Jenkins

Research Interests

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Articles (8)

Knotty is nice: Metabolite binding and RNA-mediated gene regulation by the preQ1 riboswitch family

Cyclic peptides targeting the SARS-CoV-2 programmed ribosomal frameshifting RNA from a multiplexed phage display library

Structure and function analysis of a type III preQ1-I riboswitch from E. coli reveals direct metabolite-sensing by the Shine-Dalgarno sequence

A small RNA that cooperatively senses two stacked metabolites in one pocket for gene control

A synthetic small molecule stalls pre-mRNA splicing by promoting an early-stage U2AF2-RNA complex

Representative cancer-associated U2AF2 mutations alter RNA interactions and splicing

Co-crystal structures of HIV TAR RNA bound to lab-evolved proteins show key roles for arginine relevant to the design of cyclic peptide TAR inhibitors

Analysis of a preQ1-I riboswitch in effector-free and bound states reveals a metabolite-programmed nucleobase-stacking spine that controls gene regulation

Collaborators (2)

Joseph Wedekind

Zackary Falls

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