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Jerome Moreaux

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Professor

University of Montpellier

France

Research Interests

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Recent Grants

Grant: Close

Elucidation of risk factors and health determinants associated with PROGRESSION of Monoclonal Gammopathies to Multiple Myeloma

Open Date: 2022-01-01

Close Date: 2026-01-01

Grant: Close

Lipidic control of DNA damage as therapy strategy.

Open Date: 2019-01-01

Close Date: 2022-01-01

Grant: Close

Role of three-dimensional chromatin organization and spatial co-localization during B to plasma cell differentiation – PLASMADIFF-3D

Open Date: 2018-09-20

Close Date: 2021-09-19

Grant: Close

Polycomb inhibition therapy for Multiple Myeloma.

Open Date: 2018-01-01

Close Date: 2021-01-01

Grant: Close

Towards cancer immunotherapy with “Bespoken-Antibody-Releasing B- lineage cells”

Open Date: 2018-01-01

Close Date: 2021-01-01

Articles (32)

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Collaborators (31)

Johanna Chiche

Université Côte d'Azur

FRANCE

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Ken Maes

Scientist genetic profiling of cancer

BELGIUM

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Giulia Bertolin

PI / permanent researcher

CNRS Délégation Bretagne et Pays de Loire

FRANCE

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Christof Scheid

University of Cologne

GERMANY

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Raphaël Rodriguez

Principal Investigator

CNRS Délégation Ile-de-France Sud

FRANCE

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Anne-Sophie Lia

Université de Limoges

FRANCE

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Catharina Muylaert

Vrije Universiteit Brussel

BELGIUM

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Eric Soler

Lab Head

FRANCE

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Anne Marchalot

Assistant Professor

Karolinska Institutet

SWEDEN

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Eric Rivals

Research director

Centre National de la Recherche Scientifique (CNRS)

FRANCE

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Yanmeng Wang

Vrije Universiteit Brussel

BELGIUM

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Bertrand Huard

Université Grenoble Alpes

FRANCE

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Michel Cogné

University professor

Université de Rennes 1

FRANCE

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thierry fest

university hospital of Rennes

FRANCE

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Jean‐Ehrland Ricci

Directeur de Recherche (DR1) INSERM

INSERM U1065

FRANCE

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Clement Mettling

CNRS

FRANCE

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Alexandre David

Team leader and Research Director

INSERM

FRANCE

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Hervé Técher

Chair of Professor Junior and Team Leader

Université Côte d'Azur

FRANCE

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Philippe Pasero

FRANCE

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Eline Menu

Vrije Universiteit Brussel

BELGIUM

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Anne-marie martinez

Full Professor (PRCE)

University of Montpellier

FRANCE

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Arne Wyns

Vrije Universiteit Brussel

BELGIUM

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Philip Vlummens

Vrije Universiteit Brussel

BELGIUM

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Susanne Beck

University Hospital Heidelberg

GERMANY

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Lien Ann Van Hemelrijck

Vrije Universiteit Brussel

BELGIUM

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Caroline BRET

Maître de Conférence des Universités-Praticien Hospitalier, head of the Flow Cytometry Laboratory

FRANCE

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Tatiana Cañeque

CNRS Délégation Paris B

FRANCE

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Robbe Heestermans

Vrije Universiteit Brussel

BELGIUM

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Kim De Veirman

Vrije Universiteit Brussel

BELGIUM

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Emma Verheye

Vrije Universiteit Brussel

BELGIUM

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Elke De Bruyne

Vrije Universiteit Brussel

BELGIUM

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Jerome Moreaux

Research Interests

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Recent Grants

Articles (32)

The de novo DNA methyltransferase 3B is a novel epigenetic regulator of MYC in multiple myeloma, representing a promising therapeutic target to counter relapse

Knockdown of Gene Expression Following Activation of the NMD Pathway Using Splice-Switching Oligonucleotides

Synthetic Lethal Combinations of DNA Repair Inhibitors and Genotoxic Agents to Target High-Risk Diffuse Large B Cell Lymphoma.

CD200 immune checkpoint expression is associated with inferior outcome in multiple myeloma patients treated with anti-CD38 monoclonal antibodies.

Editing B cells at the IGHA2 gene position provides alternative route to therapeutic IgA production.

Development of a robust BH3 drug toolkit for precision medicine in hematologic malignancies.

Dual targeting of EZH2 and DOT1L in DLBCL.

A case of refractory IgG4-related disease successfully treated with daratumumab and lenalidomide.

Ironomycin induces mantle cell lymphoma cell death by targeting iron metabolism addiction.

Synergistic effect of inhibiting CHK2 and DNA replication on cancer cell growth

PIM2 inhibition promotes MCL1 dependency in plasma cells involving integrated stress response-driven NOXA expression

Targeting transcription-replication conflicts using G-quadruplexes stabilizers in multiple myeloma.

S-adenosylmethionine biosynthesis is a targetable metabolic vulnerability in multiple myeloma

CD38, CD39, and BCL2 differentiate disseminated forms of high‐grade B‐cell lymphomas in biological fluids from Burkitt lymphoma and diffuse large B‐cell lymphoma

BHLHE41, a transcriptional repressor involved in physiological processes and tumor development

Quantitative Integrative Survival Prediction in Multiple Myeloma Patients Treated With Bortezomib-Based Induction, High-Dose Therapy and Autologous Stem Cell Transplantation

MRE11 and TREX1 control senescence by coordinating replication stress and interferon signaling

Extreme thrombocytosis with an aggressive evolution harboring a novel variant of calreticulin (CALR) in exon 3

Immunophenotypic portrait of leukemia‐associated‐phenotype markers in B acute lymphoblastic leukemia

3-O sulfation of syndecan-1 mediated by the sulfotransferase HS3ST3a1 enhances myeloma aggressiveness.

EZH2 targeting induces CD38 upregulation and response to anti-CD38 immunotherapies in multiple myeloma.

Var∣Decrypt: a novel and user-friendly tool to explore and prioritize variants in whole-exome sequencing data.

Targeting Cellular Iron Homeostasis with Ironomycin in Diffuse Large B-cell Lymphoma

LAIR1, an ITIM-Containing Receptor Involved in Immune Disorders and in Hematological Neoplasms

Inhibition of the Protein Arginine Methyltransferase PRMT5 in High-Risk Multiple Myeloma as a Novel Treatment Approach.

Pivotal role of PIM2 kinase in plasmablast generation and plasma cell survival, opening new treatment options in myeloma.

The NADPH oxidase NOX2 is a marker of adverse prognosis involved in chemoresistance of acute myeloid leukemias.

Targeting cellular iron homeostasis with ironomycin in diffuse large B cell lymphoma.

Comprehensive characterization of the epigenetic landscape in Multiple Myeloma.

Angiogenic factors could help us to define patients obtaining complete response with undetectable minimal residual disease in untreated CLL patients treated by FCR: results from the CLL2010FMP, a FILO study

The microenvironment of DLBCL is characterized by noncanonical macrophages recruited by tumor-derived CCL5

RNA-Sequencing-Based Transcriptomic Score with Prognostic and Theranostic Values in Multiple Myeloma

Collaborators (31)

Johanna Chiche

Ken Maes

Giulia Bertolin

Christof Scheid

Raphaël Rodriguez

Anne-Sophie Lia

Catharina Muylaert

Eric Soler

Anne Marchalot

Eric Rivals

Yanmeng Wang

Bertrand Huard

Michel Cogné

thierry fest

Jean‐Ehrland Ricci

Clement Mettling

Alexandre David

Hervé Técher

Philippe Pasero

Eline Menu

Anne-marie martinez

Arne Wyns

Philip Vlummens

Susanne Beck

Lien Ann Van Hemelrijck

Caroline BRET

Tatiana Cañeque

Robbe Heestermans

Kim De Veirman

Emma Verheye

Elke De Bruyne

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