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Elke De Bruyne

Vrije Universiteit Brussel

Belgium

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Research Interests

Cell Biology

70%

Biochemistry

40%

Multiple Myeloma

60%

Macrophage Biology

30%

Tyrosine Kinase

30%

Hematology

30%

Metabolic Biology

30%

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Articles20

The de novo DNA methyltransferase 3B is a novel epigenetic regulator of MYC in multiple myeloma, representing a promising therapeutic target to counter relapse

Article Link

Year:

2025

S-adenosylmethionine biosynthesis is a targetable metabolic vulnerability in multiple myeloma

Article Link

Year:

2024

Epigenetic Landscapes of Pain: DNA Methylation Dynamics in Chronic Pain

Article Link

Year:

2024

AXL-specific single domain antibodies show diagnostic potential and anti-tumor activity in Acute Myeloid Leukemia

Article Link

Year:

2024

AXL as immune regulator and therapeutic target in Acute Myeloid Leukemia

Article Link

Year:

2024

Bortezomib-releasing silica-collagen xerogels for local treatment of osteolytic bone- and minimal residual disease in multiple myeloma

Article Link

Year:

2024

Fueling CARs

Article Link

Year:

2024

Targeting mTOR signaling pathways in multiple myeloma

Article Link

Year:

2024

Metformin confers sensitisation to syrosingopine in multiple myeloma cells by metabolic blockage and inhibition of protein synthesis

Article Link

Year:

2023

Tasquinimod suppresses tumor cell growth and bone resorption by targeting immunosuppressive myeloid cells and inhibiting c-MYC expression in multiple myeloma

Article Link

Year:

2023

Targeting the β2 -adrenergic receptor increases chemosensitivity in multiple myeloma by induction of apoptosis and modulating cancer cell metabolism

Article Link

Year:

2023

The Biology of Stress Intolerance in Patients with Chronic Pain—State of the Art and Future Directions

Article Link

Year:

2023

Targeting S100A9 protein affects mTOR-ER stress signaling and increases venetoclax sensitivity in Acute Myeloid Leukemia

Article Link

Year:

2023

RNA-sequencing based first choice of treatment and determination of risk in multiple myeloma

Article Link

Year:

2023

Inhibition of the Protein Arginine Methyltransferase PRMT5 in High-Risk Multiple Myeloma as a Novel Treatment Approach

Article Link

Year:

2022

The prognostic value and therapeutic targeting of myeloid-derived suppressor cells in hematological cancers

Article Link

Year:

2022

Metabolic cross-talk within the bone marrow milieu

Article Link

Year:

2022

Aberrant DNA methylation in multiple myeloma

Article Link

Year:

2022

System Xc− inhibition blocks bone marrow-multiple myeloma exosomal crosstalk, thereby countering bortezomib resistance

Article Link

Year:

2022

Pyrroline-5-Carboxylate Reductase 1: a novel target for sensitizing multiple myeloma cells to bortezomib by inhibition of PRAS40-mediated protein synthesis

Article Link

Year:

2022

Collaborators29

Anke Maes

Vrije Universiteit Brussel

BELGIUM

Niels Vandewalle

Vrije Universiteit Brussel

BELGIUM

Ken Maes

Scientist genetic profiling of cancer

BELGIUM

Ann Massie

Vrije Universiteit Brussel

BELGIUM

Catharina Muylaert

Vrije Universiteit Brussel

BELGIUM

Jessica Bridoux

Vrije Universiteit Brussel

BELGIUM

Yanmeng Wang

Vrije Universiteit Brussel

BELGIUM

Jente Van Campenhout

Vrije Universiteit Brussel

BELGIUM

Ann De Becker

Vrije Universiteit Brussel

BELGIUM

Inge Oudaert

Vrije Universiteit Brussel

BELGIUM

Rong Fan

Vrije Universiteit Brussel

BELGIUM

Marcus Rohnke

GERMANY

Eline Menu

BELGIUM

Astrid Lahousse

Vrije Universiteit Brussel

BELGIUM

Gamze Ates

Vrije Universiteit Brussel

BELGIUM

Huanyu Xiong

Vrije Universiteit Brussel

BELGIUM

Arne Wyns

Vrije Universiteit Brussel

BELGIUM

Andrea Polli

Vrije Universiteit Brussel

BELGIUM

Philip Vlummens

Vrije Universiteit Brussel

BELGIUM

Lien Ann Van Hemelrijck

Vrije Universiteit Brussel

BELGIUM

Jerome Moreaux

Professor

University of Montpellier

FRANCE

Michael Gelinsky

GERMANY

Robbe Heestermans

Vrije Universiteit Brussel

BELGIUM

Kim De Veirman

Vrije Universiteit Brussel

BELGIUM

Stefaan Verhulst

Karolinska Institutet

SWEDEN

Timo De Groof

Vrije Universiteit Brussel

BELGIUM

Tu Chenggong

Vrije Universiteit Brussel

BELGIUM

Emma Verheye

Vrije Universiteit Brussel

BELGIUM

Nick Devoogdt

Vrije Universiteit Brussel

BELGIUM

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