Jesko Koehnke

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University of Glasgow

United Kingdom

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Recent Grants

Grant: Close

Investigating bottromycin biosynthesis by X-ray crystallography and in vitro engineering of the pathway

Open Date: 2014-01-01

Close Date:

Grant: Close

Structural and biochemical studies of Patellamide biosynthesis

Open Date: 2010-01-01

Close Date: 2011-12-31

Articles (13)

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2025

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2024

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2024

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2023

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2023

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2023

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2023

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2022

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2021

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2021

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2021

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Sally Shirran

University of St. Andrews

UNITED KINGDOM

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Rita Bernhardt

GERMANY

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Alexander Titz

Professor of Organic and Pharmaceutical Chemistry

Saarland University

GERMANY

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Brian Smith

Lecturer

University of Glasgow

UNITED KINGDOM

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Jesko Koehnke

Research Interests

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Recent Grants

Articles (13)

A fucose-binding superlectin from Enterobacter cloacae with high Lewis and ABO blood group antigen specificity

Trapping of a Polyketide Synthase Module after C−C Bond Formation Reveals Transient Acyl Carrier Domain Interactions

Trapping of a Polyketide Synthase Module after C−C Bond Formation Reveals Transient Acyl Carrier Domain Interactions

1-deoxy-D-xylulose-5-phosphate synthase from Pseudomonas aeruginosa and Klebsiella pneumoniae reveals conformational changes upon cofactor binding

Facile Production of the Pseudomonas aeruginosa Virulence Factor LasB in E. coli for Structure‐Based Drug Design

Unusual peptide-binding proteins guide pyrroloindoline alkaloid formation in crocagin biosynthesis

Caught in the act

Total In Vitro Biosynthesis of the Thioamitide Thioholgamide and Investigation of the Pathway

Structure‐Activity Relationship and Mode‐Of‐Action Studies Highlight 1‐(4‐Biphenylylmethyl)‐1H‐imidazole‐Derived Small Molecules as Potent CYP121 Inhibitors

Bottromycins - biosynthesis, synthesis and activity

Enhancing glycan stability via site-selective fluorination: modulating substrate orientation by molecular design

Leader peptide exchange to produce hybrid, new-to-nature ribosomal natural products

Characterization of the Stereoselective P450 Enzyme BotCYP Enables the In Vitro Biosynthesis of the Bottromycin Core Scaffold

Collaborators (9)

Michael Capper

Tim Sparwasser

Olga Kalinina

Anna Katharina Herta Hirsch

Rolf Müller

Sally Shirran

Rita Bernhardt

Alexander Titz

Brian Smith

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