Jesper Kristensen

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Københavns Universitet

Denmark

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New drug for Treatment-Resistant Depression

Open Date: 2019-01-01

Close Date: 2019-12-31

Articles (16)

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2025

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2021

Collaborators (16)

Anders Asbjørn Jensen

Professor

University of Copenhagen

DENMARK

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Rasmus Clausen

Københavns Universitet

DENMARK

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Katarzyna Targowska-Duda

Associate Professor

Medical University of Lublin

POLAND

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Claus Cornett

Københavns Universitet

DENMARK

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Anna Ulstein Odland

Københavns Universitet

DENMARK

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Kasper Harpsøe

Københavns Universitet

DENMARK

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Kristi A. Kohlmeier

Københavns Universitet

DENMARK

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Betina Elfving

Aarhus University

DENMARK

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Kassem El-Chami

Technical University of Denmark

DENMARK

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Emil Märcher-Rørsted

Københavns Universitet

DENMARK

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Katarzyna Szczepańska

Institute of Pharmacology

POLAND

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David Gloriam

Københavns Universitet

DENMARK

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Christophe Stove

Professor

Universiteit Gent

BELGIUM

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Anders Bach

Københavns Universitet

DENMARK

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Jens Soelberg

Københavns Universitet

DENMARK

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Icaro Ariel Simon

University of Amsterdam

NETHERLANDS

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Jesper Kristensen

Research Interests

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Recent Grants

Articles (16)

Synthesis, Pharmacological Characterization, and Binding Mode Analysis of 8-Hydroxy-Tetrahydroisoquinolines as 5-HT7 Receptor Inverse Agonists

The Selective 5HT2A Receptor Agonist, 25CN‐NBOH Exerts Excitatory and Inhibitory Cellular Actions on Mouse Medial Prefrontal Cortical Neurons

The Selective Serotonin 5-HT2A Receptor Agonist (S)-3-(2,5-Dimethoxy-4-(trifluoromethyl)phenyl)piperidine (LPH-5) Induces Persistent and Robust Antidepressant-Like Effects in Rodents

The Heterogeneous Kinetic Origins of the Binding Properties of Orthosteric Ligands at Heteromeric Nicotinic Acetylcholine Receptors

Discovery and Structure–Activity Relationships of 2,5-Dimethoxyphenylpiperidines as Selective Serotonin 5-HT2A Receptor Agonists

Structure–Activity Assessment and In-Depth Analysis of Biased Agonism in a Set of Phenylalkylamine 5-HT2A Receptor Agonists

Introducing Conformational Restraints on 25CN-NBOH: A Selective 5-HT2A Receptor Agonist

Overcoming Energy Transfer for the Metallophotoredox Catalyzed Decarboxylative Alkenylation between Alkylcarboxylic Acids and Enol Triflates

<i>In Vitro</i> and <i>In Vivo</i> Evaluation of Pellotine: A Hypnotic <i>Lophophora</i> Alkaloid.

Funnel metadynamics and behavioral studies reveal complex effect of D2AAK1 ligand on anxiety-like processes.

Discovery of β-Arrestin-Biased 25CN-NBOH-Derived 5-HT2A Receptor Agonists

Animal Behavior in Psychedelic Research

Erythrina Alkaloid Analogues as nAChR Antagonists–A Flexible Platform for Leads in Drug Discovery

Investigating the role of 5-HT2A and 5-HT2C receptor activation in the effects of psilocybin, DOI, and citalopram on marble burying in mice

An Improved, Scalable Synthesis of the Selective Serotonin 2A Receptor Agonist 25CN-NBOH

The Alkaloids from Lophophora diffusa and Other “False Peyotes”

Collaborators (16)

Anders Asbjørn Jensen

Rasmus Clausen

Katarzyna Targowska-Duda

Claus Cornett

Anna Ulstein Odland

Kasper Harpsøe

Kristi A. Kohlmeier

Betina Elfving

Kassem El-Chami

Emil Märcher-Rørsted

Katarzyna Szczepańska

David Gloriam

Christophe Stove

Anders Bach

Jens Soelberg

Icaro Ariel Simon

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