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Katarzyna Szczepańska

Institute of Pharmacology

Poland

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Research Interests

Pharmacology

100%

Pharmaceutical Chemistry

60%

Receptor Biology

50%

Neuropharmacology

50%

Appetite Regulation

30%

Serotonin Research

30%

Endocannabinoid

30%

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Articles12

AR71, Histamine H3 Receptor Ligand—In Vitro and In Vivo Evaluation (Anti-Inflammatory Activity, Metabolic Stability, Toxicity, and Analgesic Action)

Article Link

Year:

2024

The Effect of KSK-94, a Dual Histamine H3 and Sigma-2 Receptor Ligand, on Adipose Tissue in a Rat Model of Developing Obesity

Article Link

Year:

2024

Dual Piperidine-Based Histamine H3 and Sigma-1 Receptor Ligands in the Treatment of Nociceptive and Neuropathic Pain.

Article Link

Year:

2023

Structure-Activity Relationship and Solubility Studies of N1-Substituted Quinoxaline-2,3-diones as Kainate Receptor Antagonists.

Article Link

Year:

2023

Evaluation of Some Safety Parameters of Dual Histamine H3 and Sigma-2 Receptor Ligands with Anti-Obesity Potential

Article Link

Year:

2023

Discovery of novel arylpiperazine-based DA/5-HT modulators as potential antipsychotic agents - Design, synthesis, structural studies and pharmacological profiling.

Article Link

Year:

2023

Funnel metadynamics and behavioral studies reveal complex effect of D2AAK1 ligand on anxiety-like processes.

Article Link

Year:

2022

KSK-74: Dual Histamine H3 and Sigma-2 Receptor Ligand with Anti-Obesity Potential

Article Link

Year:

2022

Structural and Molecular Insight into Piperazine and Piperidine Derivatives as Histamine H3 and Sigma-1 Receptor Antagonists with Promising Antinociceptive Properties.

Article Link

Year:

2021

Histamine H3 Receptor Ligands-KSK-59 and KSK-73-Reduce Body Weight Gain in a Rat Model of Excessive Eating.

Article Link

Year:

2021

Metabolic benefits of novel histamine H3 receptor ligands in the model of excessive eating: The importance of intrinsic activity and pharmacokinetic properties

Article Link

Year:

2021

Discovery of Potential, Dual-Active Histamine H3 Receptor Ligands with Combined Antioxidant Properties

Article Link

Year:

2021

Collaborators14

Magdalena Kotańska

POLAND

Katarzyna Targowska-Duda

Associate Professor

Medical University of Lublin

POLAND

Michał Juszczak

Assistant professor

University of Łódź

POLAND

Marta Jóźwiak-Bębenista

Medical University of Lodz

POLAND

Tommy Johansen

Københavns Universitet

DENMARK

Jesper Kristensen

Københavns Universitet

DENMARK

Antón Leandro Martínez Rodríguez

SPAIN

Steffen Pockes

University of Regensburg

GERMANY

Anna Stasiak

Assistant Professor

Medical University of Lodz

POLAND

Waldemar Wagner

Associate Professor

Institute of Medical Biology Polish Academy of Sciences

POLAND

Katarzyna Kiec-Kononowicz

Professor, head of the Department

Uniwersytet Jagiellonski Collegium Medicum

POLAND

David Reiner-Link

Københavns Universitet

DENMARK

Enrique José Cobos Del Moral

Universidad de Granada

SPAIN

Katarzyna Woźniak

University of Łódź

POLAND

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Katarzyna Szczepańska

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Research Interests

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Articles12

AR71, Histamine H<sub>3</sub> Receptor Ligand—In Vitro and In Vivo Evaluation (Anti-Inflammatory Activity, Metabolic Stability, Toxicity, and Analgesic Action)

The Effect of KSK-94, a Dual Histamine H3 and Sigma-2 Receptor Ligand, on Adipose Tissue in a Rat Model of Developing Obesity

Dual Piperidine-Based Histamine H<sub>3</sub> and Sigma-1 Receptor Ligands in the Treatment of Nociceptive and Neuropathic Pain.

Structure-Activity Relationship and Solubility Studies of N1-Substituted Quinoxaline-2,3-diones as Kainate Receptor Antagonists.

Evaluation of Some Safety Parameters of Dual Histamine H<sub>3</sub> and Sigma-2 Receptor Ligands with Anti-Obesity Potential

Discovery of novel arylpiperazine-based DA/5-HT modulators as potential antipsychotic agents - Design, synthesis, structural studies and pharmacological profiling.

Funnel metadynamics and behavioral studies reveal complex effect of D2AAK1 ligand on anxiety-like processes.

KSK-74: Dual Histamine H<sub>3</sub> and Sigma-2 Receptor Ligand with Anti-Obesity Potential

Structural and Molecular Insight into Piperazine and Piperidine Derivatives as Histamine H<sub>3</sub> and Sigma-1 Receptor Antagonists with Promising Antinociceptive Properties.

Histamine H3 Receptor Ligands-KSK-59 and KSK-73-Reduce Body Weight Gain in a Rat Model of Excessive Eating.

Metabolic benefits of novel histamine H3 receptor ligands in the model of excessive eating: The importance of intrinsic activity and pharmacokinetic properties

Discovery of Potential, Dual-Active Histamine H3 Receptor Ligands with Combined Antioxidant Properties

Collaborators14

Magdalena Kotańska

Katarzyna Targowska-Duda

Michał Juszczak

Marta Jóźwiak-Bębenista

Tommy Johansen

Jesper Kristensen

Antón Leandro Martínez Rodríguez

Steffen Pockes

Anna Stasiak

Waldemar Wagner

Katarzyna Kiec-Kononowicz

David Reiner-Link

Enrique José Cobos Del Moral

Katarzyna Woźniak

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