Jess G. Snedeker

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Balgrist University Hospital

Switzerland

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Recent Grants

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From Cells to Tissues: A lattice light sheet microscope to improve spatiotemporal resolution

Open Date: 2019-10-01

Close Date: 2020-09-30

Grant: Close

Mechanically triggered calcium influx - Seeking the molecular limit switch of the tendon mechanostat

Open Date: 2019-04-01

Close Date: 2022-03-31

Grant: Close

3D-LEDECO: SIMULATION-BASED SURGICAL PLANNING FOR OPTIMIZED LEG DEFORMITY CORRECTION UNDER CONSIDERATION OF WEIGHT-BEARING AND JOINT LOAD

Open Date: 2019-01-01

Close Date: 2022-12-31

Grant: Close

Sub-micrometre-scale 3D Chemical Characterization of Organic and Biological Materials

Open Date: 2016-04-01

Close Date: 2019-03-31

Grant: Close

Advanced microscopy for direct observation of tendon cell and tissue mechanotransduction

Open Date: 2016-04-01

Close Date: 2019-03-31

Articles (19)

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2024

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2023

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2023

The E756del gene variant causes overactivity of the mechanosensitive membrane channel PIEZO1 and is suspected to upregulate tendon collagen cross linking. In human carriers of E756del, we found increased patellar tendon stiffness but similar tendon lengths and cross-sectional areas, directly supporting the premise that PIEZO1 regulates human tendon stiffness at the level of tissue material properties.

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2023

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2023

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2023

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2023

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2023

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2023

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2023

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2023

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2023

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2022

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2022

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2022

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2022

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2022

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2022

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2022

Collaborators (14)

Johanna Buschmann

Lecturer for "Medizin + Technik" (MA)

University of Zurich

SWITZERLAND

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Fabio Carrillo

Head of Research Unit

SWITZERLAND

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Lukas Sommer

Professor

University of Zurich

SWITZERLAND

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Alen Pavlic

ETH Zürich

SWITZERLAND

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Hooman Esfandiari

Balgrist University Hospital

SWITZERLAND

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Jörg Spörri

Balgrist University Hospital

SWITZERLAND

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Corinne Tanchot

Université Paris Cité

FRANCE

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Mazda Farshad

Balgrist University Hospital

SWITZERLAND

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Philipp Fürnstahl

Assistant Professor

University of Zurich

SWITZERLAND

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Amro Hussien

Max Planck Institute of Molecular Physiology

GERMANY

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Maurizio Calcagni

University Hospital of Zurich

SWITZERLAND

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Franz E. Weber

University of Zurich

SWITZERLAND

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Jurg Dual

Prof. Dr.

ETH Zürich

SWITZERLAND

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Eileen Gentleman

Professor of Bioengineering

King’s College London

UNITED KINGDOM

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Jess G. Snedeker

Research Interests

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Recent Grants

Articles (19)

Automatic registration with continuous pose updates for marker-less surgical navigation in spine surgery

Sharp-edge-based acoustofluidic chip capable of programmable pumping, mixing, cell focusing, and trapping

Bioactive and Elastic Emulsion Electrospun DegraPol Tubes Delivering IGF-1 for Tendon Rupture Repair

PIEZO1 gain-of-function gene variant is associated with elevated tendon stiffness in humans

The Stiffness‐Sensitive Transcriptome of Human Tendon Stromal Cells

An automated optimization pipeline for clinical-grade computer-assisted planning of high tibial osteotomies under consideration of weight-bearing

Automatic 3D Postoperative Evaluation of Complex Orthopaedic Interventions

Correction: Posterior stability of the shoulder depends on acromial anatomy: a biomechanical study of 3D surface models.

Three-dimensional mapping of ultrasound-derived skeletal muscle shear wave velocity.

Rotator Cuff Repair and Overlay Augmentation by Direct Interlocking of a Nonwoven Polyethylene Terephthalate Patch Into the Tendon: Evaluation in an Ovine Model.

Structural Musculotendinous Parameters That Predict Failed Tendon Healing After Rotator Cuff Repair.

Guidelines for ex vivo mechanical testing of tendon.

Engineered hydrogels for mechanobiology

A novel approach for tetrahedral-element-based finite element simulations of anisotropic hyperelastic intervertebral disc behavior.

Investigation of the relationship between tensile viscoelasticity and unloaded ultrasound shear wave measurements in ex vivo tendon.

Biomechanical Analysis of Posterior Open-Wedge Osteotomy and Glenoid Concavity Reconstruction Using an Implant-Free, J-Shaped Iliac Crest Bone Graft.

FGF2 overrides key pro-fibrotic features of bone marrow stromal cells isolated from Modic type 1 change patients.

Vaccination-based immunotherapy to target profibrotic cells in liver and lung.

Deepening trochleoplasty may dramatically increase retropatellar contact pressures- a pilot study establishing a finite element model.

Collaborators (14)

Johanna Buschmann

Fabio Carrillo

Lukas Sommer

Alen Pavlic

Hooman Esfandiari

Jörg Spörri

Corinne Tanchot

Mazda Farshad

Philipp Fürnstahl

Amro Hussien

Maurizio Calcagni

Franz E. Weber

Jurg Dual

Eileen Gentleman

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