Jessica Downs

Professor

Institute of Cancer Research

United Kingdom

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Articles (9)

Year:

2022

Year:

2022

Year:

2021

Year:

2021

Year:

2021

Year:

2021

Year:

2020

Year:

2020

Year:

2020

Collaborators (10)

Andrew Flaus

University of Galway

IRELAND

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Fabrice Gielen

UNITED KINGDOM

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Frances Pearl

University of Sussex School of Life Sciences

UNITED KINGDOM

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Tom Owen-Hughes

Professor

University of Dundee

UNITED KINGDOM

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Fiona Errington-Mais

Associate Professor of Cancer Immunology

University of Leeds

UNITED KINGDOM

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Dan Bottomley

University of Leeds

UNITED KINGDOM

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Roman M. Chabanon

Post-doctoral research fellow

Institute of Cancer Research

UNITED KINGDOM

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Marko Hyvönen

University of Cambridge

UNITED KINGDOM

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Hugang Feng

The Francis Crick Institute

UNITED KINGDOM

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Mercedes Pardo

Institute of Cancer Research

UNITED KINGDOM

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Jessica Downs

Research Interests

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Articles (9)

Aneuploidy tolerance caused by BRG1 loss allows chromosome gains and recovery of fitness

PBAF loss leads to DNA damage-induced inflammatory signaling through defective G2/M checkpoint maintenance.

Differential and longitudinal immune gene patterns associated with reprogrammed microenvironment and viral mimicry in response to neoadjuvant radiotherapy in rectal cancer

Improved RAD51 binders through motif shuffling based on the modularity of BRC repeats.

PBRM1 Deficiency Confers Synthetic Lethality to DNA Repair Inhibitors in Cancer.

TP53 modulates radiotherapy fraction size sensitivity in normal and malignant cells.

Histone isoforms and the oncohistone code.

CHD7 and 53BP1 regulate distinct pathways for the re-ligation of DNA double-strand breaks.

The role of the SWI/SNF chromatin remodelling complex in the response to DNA double strand breaks.

Collaborators (10)

Andrew Flaus

Fabrice Gielen

Frances Pearl

Tom Owen-Hughes

Fiona Errington-Mais

Dan Bottomley

Roman M. Chabanon

Marko Hyvönen

Hugang Feng

Mercedes Pardo

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