John Crown

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St. Vincent's University Hospital

Ireland

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Recent Grants

Grant: Close

GDEFINER: Gender Difference In sidE eFfects of ImmuNotherapy: a possible clue to optimize cancER treatment

Open Date: 2019-01-01

Close Date: 2021-12-31

Grant: Close

Gender difference in Side effects of immunotherapy: a possible clue to optimize cancer treatment

Open Date: 2019-01-01

Close Date:

Grant: Close

Characterisaation of the mutational status of a large panel of genes in newly diagnosed patients with solid tumours

Open Date: 2012-01-01

Close Date: 2012-12-31

Grant: Close

National Cancer Research Centre of Ireland (NCRCI) Workshop

Open Date: 2012-01-01

Close Date:

Grant: Close

Investigation of exosomes and extracellular miRNAs as potential biomarkers for prostate cancer

Open Date: 2012-01-01

Close Date: 2012-12-31

Articles (10)

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2021

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2020

Collaborators (6)

Darran O'Connor

Professor

Royal College of Surgeons in Ireland

IRELAND

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Jonas Bergh

Karolinska University Hospital

SWEDEN

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Alex Eustace

Assistant Professor in Biotechnology

Dublin City University

IRELAND

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Denis Collins

Assistant Professor / PI Cancer Biotherapeutics Research Group

Dublin City University

IRELAND

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William Watson

Full Professor of Cancer Biology

Dublin City University

IRELAND

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Kathy Gately

Clinical Senior Lecturer

Trinity College Dublin

IRELAND

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John Crown

Research Interests

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Recent Grants

Articles (10)

First use of tofacitinib to treat an immune checkpoint inhibitor-induced arthritis.

A phase Ib/II study of xentuzumab, an IGF-neutralising antibody, combined with exemestane and everolimus in hormone receptor-positive, HER2-negative locally advanced/metastatic breast cancer.

Comparative analysis of drug response and gene profiling of HER2-targeted tyrosine kinase inhibitors.

MYC as a target for cancer treatment.

The novel low molecular weight MYC antagonist MYCMI-6 inhibits proliferation and induces apoptosis in breast cancer cells.

Inhibition of Serum Response Factor Improves Response to Enzalutamide in Prostate Cancer.

Pembrolizumab plus chemotherapy versus placebo plus chemotherapy for previously untreated locally recurrent inoperable or metastatic triple-negative breast cancer (KEYNOTE-355): a randomised, placebo-controlled, double-blind, phase 3 clinical trial.

Effects of HER Family-targeting Tyrosine Kinase Inhibitors on Antibody-dependent Cell-mediated Cytotoxicity in HER2-expressing Breast Cancer.

Drugging "undruggable" genes for cancer treatment: Are we making progress?

Differential Benefit of Adjuvant Docetaxel-Based Chemotherapy in Patients With Early Breast Cancer According to Baseline Body Mass Index.

Collaborators (6)

Darran O'Connor

Jonas Bergh

Alex Eustace

Denis Collins

William Watson

Kathy Gately

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