John Tesmer

Walther Professor in Cancer Structural Biology

Purdue University

United States

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Articles (9)

Year:

2022

Year:

2022

Year:

2021

Year:

2021

Year:

2020

Year:

2020

Year:

2020

Year:

2020

Year:

2020

Collaborators (8)

Martin Gustavsson

Københavns Universitet

DENMARK

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Robert Stahelin

Retter Professor of Pharmacy

Purdue University

UNITED STATES

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Qing Deng

Associate Professor

Purdue University

UNITED STATES

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Sang Yeop Kim

University of Michigan

UNITED STATES

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Varun Gadkari

Assistant Professor

University of Minnesota

UNITED STATES

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Tyler Beyett

Assistant Professor

Emory University

UNITED STATES

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Manojkumar Puthenveedu

Associate Professor

University of Michigan

UNITED STATES

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Christopher Schafer

Assistant Professor

University of Amsterdam

NETHERLANDS

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John Tesmer

Research Interests

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Articles (9)

Structures of atypical chemokine receptor 3 reveal the basis for its promiscuity and signaling bias

Biochemical characterization of the interaction between KRAS and Argonaute 2

The Open Question of How GPCRs Interact with GPCR Kinases (GRKs)

Generation of Highly Selective, Potent, and Covalent G Protein-Coupled Receptor Kinase 5 Inhibitors

A New Paroxetine-Based GRK2 Inhibitor Reduces Internalization of the μ-Opioid Receptor

Discovery of Small Molecules That Target the Phosphatidylinositol (3,4,5) Trisphosphate (PIP3)-Dependent Rac Exchanger 1 (P-Rex1) PIP3-Binding Site and Inhibit P-Rex1–Dependent Functions in Neutrophils

The first DEP domain of the RhoGEF P-Rex1 autoinhibits activity and contributes to membrane binding

A Global Map of G Protein Signaling Regulation by RGS Proteins

Phospholipid Component Defines Pharmacokinetic and Pharmacodynamic Properties of Synthetic High-Density Lipoproteins

Collaborators (8)

Martin Gustavsson

Robert Stahelin

Qing Deng

Sang Yeop Kim

Varun Gadkari

Tyler Beyett

Manojkumar Puthenveedu

Christopher Schafer

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