John W R Schwabe

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University of Leicester

United Kingdom

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Grant: Open

Understanding the diverse molecular mechanisms of chromatin-targeted histone deacetylase complexes

Open Date: 2021-11-01

Close Date: 2026-10-31

Articles (10)

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2023

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2022

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2021

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2021

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2021

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2020

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2020

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2020

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2020

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2020

Collaborators (9)

Ilaria Gentile

University of Milan

ITALY

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Xu Xiao

Assistant Professor

University of Kentucky

UNITED STATES

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Alan Roseman

The University of Manchester

UNITED KINGDOM

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Zhipeng Wang

Assistant Professor

Sylvester Comprehensive Cancer Center

UNITED STATES

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Cyril Dominguez

Associate professor

University of Leicester

UNITED KINGDOM

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Krishna Chatterjee

University of Cambridge

UNITED KINGDOM

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Robert Lahue

Professor

National University of Ireland Galway

IRELAND

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Mark Collins

University of Sheffield

UNITED KINGDOM

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James Hodgkinson

Lecturer

University of Leicester

UNITED KINGDOM

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John W R Schwabe

Research Interests

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Contact this professor

Recent Grants

Articles (10)

A potential histone-chaperone activity for the MIER1 histone deacetylase complex

Histone H2B Deacylation Selectivity: Exploring Chromatin's Dark Matter with an Engineered Sortase.

Structure-Guided Approach to Relieving Transcriptional Repression in Resistance to Thyroid Hormone α.

Cryo-EM structural analysis of FADD:Caspase-8 complexes defines the catalytic dimer architecture for co-ordinated control of cell fate

Selective Aster inhibitors distinguish vesicular and nonvesicular sterol transport mechanisms.

HDAC3 deacetylates the DNA mismatch repair factor MutSβ to stimulate triplet repeat expansions

The topology of chromatin-binding domains in the NuRD deacetylase complex

HYPERTHYROXINEMIA AND HYPERCORTISOLEMIA DUE TO FAMILIAL DYSALBUMINEMIA.

Diverse nucleosome Site-Selectivity among histone deacetylase complexes

The MiDAC histone deacetylase complex is essential for embryonic development and has a unique multivalent structure.

Collaborators (9)

Ilaria Gentile

Xu Xiao

Alan Roseman

Zhipeng Wang

Cyril Dominguez

Krishna Chatterjee

Robert Lahue

Mark Collins

James Hodgkinson

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