jonathan brown

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Assistant Professor

Vanderbilt University Medical Center

United States

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About

Jonathan Brown is an Assistant Professor at Vanderbilt University Medical Center in the United States. His research focuses on cardiometabolic disease, liver fibrosis, and the regulation of immune responses, as evidenced by his recent publications. Notable articles include investigations into the bone marrow niche's therapeutic potential and the role of transcription factors in collagen production and hypertensive conditions.

Recent Grants

Grant: Close

DNA Base Editing as a Therapeutic Strategy in Hutchinson-Gilford Progeria Syndrome

Open Date: 2021-01-01

Close Date: 2024-12-31

Grant: Close

Elucidating the chromatin-dependent mechanisms governing chronic inflammatory activation of endothelial cells in atherosclerosis

Open Date: 2020-04-01

Close Date: 2024-03-01

Articles (15)

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2025

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2022

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2021

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2021

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2021

Collaborators (12)

Matthew Steinhauser

University of Pittsburgh School of Medicine

UNITED STATES

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Vanderbilt University Medical Center

UNITED STATES

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Dmytro Kryshtal

Research Assistant Professor

Vanderbilt University Medical Center

UNITED STATES

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MacRae Linton

Professor of Medicine

Vanderbilt University Medical Center

UNITED STATES

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W Gray Jerome

Professor

Vanderbilt University Medical Center

UNITED STATES

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Heather Caslin

Assistant Professor

University of Houston

UNITED STATES

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jonathan brown

Research Interests

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About

Recent Grants

Articles (15)

Bone Marrow Niche in Cardiometabolic Disease: Mechanisms and Therapeutic Potential

The transcription factor ZNF469 regulates collagen production in liver fibrosis

Article Transcriptional synergy in human aortic endothelial cells is vulnerable to combination p300/CBP and BET bromodomain inhibition

Trained Immunity Impairs Inflammation Resolution And Dampens Efferocytosis

Angiotensin II-induced Hypertension Promotes Innate Immune Memory And Predisposes To Atherosclerosis Progression

Nanoscale imaging of DNA-RNA identifies transcriptional plasticity at heterochromatin

The consumption of animal products is associated with plasma levels of alpha-aminoadipic acid (2-AAA)

The transcription factor ZNF469 regulates collagen production in liver fibrosis

Transcriptional Dysregulation Underlies Both Monogenic Arrhythmia Syndrome and Common Modifiers of Cardiac Repolarization

Association of alpha-aminoadipic acid (2-AAA) with cardiometabolic risk factors in healthy and high-risk individuals

Association of alpha-aminoadipic acid with cardiometabolic risk factors in healthy and high-risk individuals

The FoxOs are in the ApoM house

Macrophage SR-BI modulates autophagy via VPS34 complex and PPARα transcription of Tfeb in atherosclerosis

Base editor treats progeria in mice

Targeting the Apoa1 locus for liver-directed gene therapy

Collaborators (12)

Matthew Steinhauser

Luke Koblan

Marco De Giorgi

Jonathan Mosley

Andrew Glazer

Kasey Vickers

Patricia Yancey

Amanda C. Doran

Dmytro Kryshtal

MacRae Linton

W Gray Jerome

Heather Caslin

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