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João Peça

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Assistant Professor

University of Coimbra

Portugal

Research Interests

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About

João Peça is an Assistant Professor at the University of Coimbra, Portugal. His research focuses on neurodevelopment and brain editing techniques, with recent publications exploring topics such as microglial changes due to early-life interventions, genetic variants associated with severe epilepsy, and innovative applications of CRISPR-Cas9 for brain gene editing. He also investigates maternal behaviors impacting neurodevelopmental trajectories and the engineering of tools for brain stimulation and regeneration.

Recent Grants

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The role of IL-4 and allergies in life-long neural rewiring and dementia

Open Date: 2026-01-01

Close Date:

Grant: Close

F.O.C.U.S: The Role of Front-Orbito-Cerebellar Unity in Sustained Motivation

Open Date: 2025-04-15

Close Date:

Grant: Close

Focus on Science: Attention, Attention, Attention!

Open Date: 2024-05-01

Close Date: 2024-12-01

Grant: Close

ELEANA: Early-Life Environmental AllergeNs in ADHD

Open Date: 2024-04-09

Close Date: 2025-12-01

Grant: Close

Th2brain: Effects of Th2-related immunity in the postnatal maturation of brain circuits

Open Date: 2023-01-01

Close Date:

Articles (20)

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2021

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2021

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2021

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2020

Collaborators (28)

Aranzazu Diaz Cuenca

Principal Investigator

Consejo Superior de Investigaciones Cientificas

SPAIN

João Peça

Research Interests

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About

Recent Grants

Articles (20)

3D-Printed and Bioprinted Scaffolds in Regenerative Endodontics: A Systematic Review

Histological Tissue Response to Calcium Silicate-Based Cements Assessed in Human Tooth Culture Models: A Systematic Review

Early‐life IL‐4 administration induces long‐term changes in microglia in the cerebellum and prefrontal cortex

Mesenchymal stromal cell secretome-induced synaptogenesis is mediated by thrombospondin-1

Maternal behaviours disrupted by Gprasp2 deletion modulate neurodevelopmental trajectory in progeny

Near-Infrared Light Activated Formulation for the Spatially Controlled Release of CRISPR-Cas9 Ribonucleoprotein for Brain Gene Editing

A Novel Genetic Variant in MBD5 Associated with Severe Epilepsy and Intellectual Disability: Potential Implications on Neural Primary Cilia

Engineering optical tools for remotely controlled brain stimulation and regeneration

In vivo recordings in freely behaving mice using independent silicon probes targeting multiple brain regions

IL-4 shapes microglia-dependent pruning of the cerebellum during postnatal development

Brain Gain – Discovering Neurosciences: A digital education outreach project for higher education students

Scaffolds for Dentin–Pulp Complex Regeneration

Attenuation of Autism-like Behaviors by an Anthocyanin-Rich Extract from Portuguese Blueberries via Microbiota–Gut–Brain Axis Modulation in a Valproic Acid Mouse Model

Efficient spatially targeted gene editing using a near-infrared activatable protein-conjugated nanoparticle for brain applications

Microglia‐dependent remodeling of neuronal circuits

Generation and Characterization of Novel iPSC Lines from a Portuguese Family Bearing Heterozygous and Homozygous GRN Mutations

Ligand-independent activity of the ghrelin receptor modulates AMPA receptor trafficking and supports memory formation.

The old guard: Age-related changes in microglia and their consequences

Regeneration of pulp-dentin complex using human stem cells of the apical papilla: in vivo interaction with two bioactive materials

Distinct subnetworks of the thalamic reticular nucleus

Collaborators (28)

Aranzazu Diaz Cuenca

Stefan Stricker

Ramiro Almeida

Carlos B. Duarte

Juan J Segura-Egea

Vitor Paiva

Jenifer Martin-Gonzalez

lino ferreira

Daniel Choquet

Pedro Martins Carvalho

Diana Serra

Rita Campos

Sara Varela Amaral

Mário Carvalho

Diana B. Sequeira

Filipe Martinho

Victor Freitas

João Miguel Marques dos Santos

Frederico Duque

Michael Halassa

Patricio Opazo

Paulo J. Palma

Catarina Morais Seabra

Ana Carolina Bione Kunicki Peres

Sonia Pinho

Gabriela Jorge Da Silva

Guiomar Oliveira

Ana Luisa Carvalho

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