Jorge A. R. Salvador

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University of Coimbra

Portugal

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Recent Grants

Grant: Close

Strategic Plan -Center for Innovative Biomedicine and Biotechnology

Open Date: 2020-01-01

Close Date: 2023-01-01

Grant: Close

Srategic Plan-Institute for Biomedical Imaging and Translational Research UIDB/04950/2020

Open Date: 2020-01-01

Close Date: 2023-01-01

Grant: Close

Strategic Plan-Centro de Química de Coimbra Coimbra Chemistry Center UIDB/00313/2020

Open Date: 2020-01-01

Close Date: 2023-01-01

Grant: Close

Projects for the Development and Implementation of Research Infrastructures inserted in the ESFRI. National Mass Spectrometry Network. UC node .

Open Date: 2017-01-01

Close Date: 2021-01-01

Grant: Close

Drugs2CAD-Treatment of cancer and Alzheimer's diseases: discovering new drugs. Ref. CENTRO-01-0247-FEDER-003269

Open Date: 2016-01-01

Close Date: 2020-01-01

Articles (19)

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2022

Collaborators (13)

Andreia Neves Carvalho

Assistant Professor (Invited)

Faculty of Pharmacy, University of Lisbon

PORTUGAL

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Adriana Oliveira dos Santos

Assistant Professor

Universidade da Beira Interior

PORTUGAL

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Adelaide Fernandes

Assistant Professor

Universidade de Lisboa Faculdade de Farmácia

PORTUGAL

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Rita C. Guedes

Universidade de Aveiro

PORTUGAL

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Mariana Matias

Guest Auxiliar Professor

Universidade da Beira Interior

PORTUGAL

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Nuria Gomez

Instituto de Investigación Sanitaria La Fe

SPAIN

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Natália Aniceto

Professor of Pharmacokinetics

University of Lisbon

PORTUGAL

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Vânia Moreira

Assistant Professor

University of Coimbra

PORTUGAL

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Helena F Florindo

Associate Professor with habilitation

Faculty of Pharmacy, University of Lisbon

PORTUGAL

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Samuel Silvestre

Associate Professor

Universidade da Beira Interior

PORTUGAL

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Romina Guedes

Invited Assistant Professor

Universidade de Lisboa Faculdade de Farmácia

PORTUGAL

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Paula Leandro

Assistant Professor

Universidade de Lisboa Faculdade de Farmácia

PORTUGAL

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Maryam Abbasi

Assistant Invited Professor

Instituto Politécnico de Coimbra Instituto Superior de Engenharia de Coimbra

PORTUGAL

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Jorge A. R. Salvador

Research Interests

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Contact this professor

Recent Grants

Articles (19)

Synthesis, biological evaluation and clinical trials of Cereblon-based PROTACs

BACE1 Inhibitors for Alzheimer’s Disease: Current Challenges and Future Perspectives

PROteolysis‐Targeting Chimeras (PROTACs) in leukemia: overview and future perspectives

Bioactive Bismuth Compounds: Is Their Toxicity a Barrier to Therapeutic Use?

Decoding the secrets: how conformational and structural regulators inhibit the human 20S proteasome

Design, Synthesis, and Biological Evaluation of Novel Urea-Containing Carnosic Acid Derivatives with Anticancer Activity

Bi- and tricyclic diterpenoids: landmarks from a decade (2013–2023) in search of leads against infectious diseases

New Scaffolds of Proteasome Inhibitors: Boosting Anticancer Potential by Exploiting the Synergy of In Silico and In Vitro Methodologies

Design, synthesis, and biological evaluation of new arjunolic acid derivatives as anticancer agents

Ubiquitin-specific protease 7 (USP7): an emerging drug target for cancer treatment

Proteolysis-Targeting Chimeras (PROTACs) targeting the BCR-ABL for the treatment of chronic myeloid leukemia – a patent review

Therapeutic potential of glutaminyl cyclases: Current status and emerging trends

Recent advances in oridonin derivatives with anticancer activity

Artificial intelligence for prediction of biological activities and generation of molecular hits using stereochemical information

Therapeutic targeting of PD-1/PD-L1 blockade by novel small-molecule inhibitors recruits cytotoxic T cells into solid tumor microenvironment

Deep generative model for therapeutic targets using transcriptomic disease-associated data-USP7 case study.

Revisiting Proteasome Inhibitors: Molecular Underpinnings of Their Development, Mechanisms of Resistance and Strategies to Overcome Anti-Cancer Drug Resistance

MDM2-Based Proteolysis-Targeting Chimeras (PROTACs): An Innovative Drug Strategy for Cancer Treatment

Highlights in USP7 inhibitors for cancer treatment

Collaborators (13)

Andreia Neves Carvalho

Adriana Oliveira dos Santos

Adelaide Fernandes

Rita C. Guedes

Mariana Matias

Nuria Gomez

Natália Aniceto

Vânia Moreira

Helena F Florindo

Samuel Silvestre

Romina Guedes

Paula Leandro

Maryam Abbasi

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