Romina Guedes

Invited Assistant Professor

Universidade de Lisboa Faculdade de Farmácia

Portugal

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Research Interests

Biochemistry

50%

Cell Biology

30%

Cancer Biology

30%

Proteasome Biology

30%

Ubiquitin

30%

Bioinformatics

20%

Chemical Biology

20%

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Recent Grants

Grant: Close

Small-molecule inhibitors of human proteasome: a step forward in anticancer drug discovery

Open Date: 2015-05-01

Close Date: 2019-12-31

Grant: Close

Targeting the proteasome in anticancer therapy through a computational based drug discovery approach

Open Date: 2015-03-02

Close Date: 2019-03-01

Grant: Close

Targeting the proteasome in anticancer therapy by a computational based drug discovery approach

Open Date: 2015-01-01

Close Date: 2019-02-01

Grant: Close

Small-molecule inhibitors of human proteasome: a step forward in anticancer drug discovery

Open Date:

Close Date:

Grant: Close

Funding of RD Units Strategic Plan - 2013/2015 - OE

Open Date:

Close Date:

Articles8

Decoding the secrets: how conformational and structural regulators inhibit the human 20S proteasome

Article Link

Year:

2024

New Scaffolds of Proteasome Inhibitors: Boosting Anticancer Potential by Exploiting the Synergy of In Silico and In Vitro Methodologies

Article Link

Year:

2023

Artificial intelligence for prediction of biological activities and generation of molecular hits using stereochemical information

Article Link

Year:

2023

Disclosing the antitumour potential of the marine bromoditerpene sphaerococcenol A on distinct cancer cellular models

Article Link

Year:

2022

Bromoditerpenes from the Red Seaweed Sphaerococcus coronopifolius as Potential Cytotoxic Agents and Proteasome Inhibitors and Related Mechanisms of Action

Article Link

Year:

2022

Deep generative model for therapeutic targets using transcriptomic disease-associated data-USP7 case study.

Article Link

Year:

2022

Revisiting Proteasome Inhibitors: Molecular Underpinnings of Their Development, Mechanisms of Resistance and Strategies to Overcome Anti-Cancer Drug Resistance

Article Link

Year:

2022

Highlights in USP7 inhibitors for cancer treatment

Article Link

Year:

2022

Collaborators12

Celso Alves

Guest Assistant - Lecturer

Instituto Politécnico de Leiria Escola Superior de Turismo e Tecnologia do Mar de Peniche

PORTUGAL

Marta Afonso

Assistant Professor

Faculty of Pharmacy, University of Lisbon

PORTUGAL

Adriana Oliveira dos Santos

Assistant Professor

Universidade da Beira Interior

PORTUGAL

Luis Botana

Universidade de Santiago de Compostela

SPAIN

Rita C. Guedes

Universidade de Aveiro

PORTUGAL

Maria Amparo Alfonso Rancaño

Profesora Titular de Universidad

Universidade de Santiago de Compostela

SPAIN

Rui Pedrosa

Coordinator Professor

Instituto Politécnico de Leiria

PORTUGAL

Marcia Ines Goettert

Researcher- assistant Professor

University of Tuebingen

GERMANY

Samuel Silvestre

Associate Professor

Universidade da Beira Interior

PORTUGAL

Helena Gaspar

Assistant Professor

University of Lisbon

PORTUGAL

Jorge A. R. Salvador

University of Coimbra

PORTUGAL

Maryam Abbasi

Assistant Invited Professor

Instituto Politécnico de Coimbra Instituto Superior de Engenharia de Coimbra

PORTUGAL

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