Jose Antonio Lopez-Escamez

Professor of Meniere disease Neuroscience

University of Sydney

Australia

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About

Professor Jose Antonio Lopez-Escamez is a leading researcher in Meniere disease neuroscience at the University of Sydney, Australia. His research focuses on the genetic and molecular mechanisms underlying Meniere's disease, including the role of missense and loss-of-function variants, DNA methylation profiles, and the pathophysiology of the condition. He has recently contributed to systematic reviews and studies exploring the genetic structures and developing preclinical models to further understanding and potential therapies for Meniere's disease.

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2022

Collaborators (5)

Angel Batuecas Caletrio

Profesor Titular / Senior Lecturer

SPAIN

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Andrés Soto-Varela

Jefe de Servicio y Profesor Titular

Servicio Andaluz de Salud

SPAIN

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Lidia Frejo

SPAIN

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Natalia Trpchevska

Karolinska Institutet

SWEDEN

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Patricia Perez-Carpena

Profesor Permanente Laboral

Universidad de Granada

SPAIN

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Jose Antonio Lopez-Escamez

Research Interests

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About

Articles (20)

Different Contribution of Missense and Loss‐of‐Function Variants to the Genetic Structure of Familial and Sporadic Meniere Disease

Whole genome DNA methylation profiles define Meniere’s disease subclusters

A Systematic Review on the Role of the Stria Vascularis in Menière’s Disease Pathogenesis

Dissecting the genome in Ménière disease: a review

Prevalence of the endolymphatic sac hypoplasia in a cohort of individuals without Meniere disease

Replication of Missense OTOG Gene Variants in a Brazilian Patient with Menière’s Disease

An ultra-rare missense variant in the KIF1B gene linked to autoinflammatory Menière’s disease

A Neuron-Like Cellular Model for Severe Tinnitus Associated with Rare Variations in the ANK2 Gene

The effect of camera side on the VOR gain in video head impulse test

Preclinical Models to Study the Molecular Pathophysiology of Meniere’s Disease: A Pathway to Gene Therapy

Immune‐Related Disorders Associated With Ménière's Disease: A Systematic Review and Meta‐analysis

Types of Inheritance and Genes Associated with Familial Meniere Disease

Rare Coding Variants in Patients with Non-Syndromic Vestibular Dysfunction

Application of Human Stem Cells to Model Genetic Sensorineural Hearing Loss and Meniere Disease

Magnetic resonance imaging of endolymphatic hydrops: Controversies and common ground, comment on: "A plea for systematic literature analysis and conclusive study design"

Using coding and non-coding rare variants to target candidate genes in patients with severe tinnitus.

A novel nonsense variant in the CENPP gene segregates in a Swiss family with autosomal dominant low-frequency sensorineural hearing loss

Technological Advances in the Diagnosis and Management of Tinnitus

Defective α-tectorin may involve tectorial membrane in familial Meniere disease.

A Predictive Model of Bilateral Sensorineural Hearing Loss in Meniere Disease Using Clinical Data.

Collaborators (5)

Angel Batuecas Caletrio

Andrés Soto-Varela

Lidia Frejo

Natalia Trpchevska

Patricia Perez-Carpena

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