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Jose Carlos Machado

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Principal Investigator

i3S - Instituto de Investigação e Inovação em Saúde, Universidade do Porto

Portugal

Research Interests

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Professors in Portugal Professors in Cell Biology Cell Biology professors in Portugal

Recent Grants

Grant: Close

Glycosylation and cancer: immunosurveillance’s sweet spot

Open Date: 2022-01-01

Close Date: 2023-06-30

Grant: Close

Circulating Microbial Signatures for Early Diagnosis of Cancer

Open Date: 2022-01-01

Close Date: 2024-12-31

Grant: Close

Institute for Research and Innovation in Health

Open Date: 2021-01-01

Close Date: 2025-12-31

Grant: Close

Institute for Research and Innovation in Health Sciences

Open Date: 2019-01-01

Close Date: 2019-12-31

Grant: Close

Neoantigen signature algorithm to predict immunotherapy response

Open Date: 2018-01-01

Close Date:

Articles (20)

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Collaborators (27)

Óscar Núñez

Profesor asociado Facultad de Medicina

Universidad CEU San Pablo

SPAIN

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Hector Peinado

Associate Professor - Investigador Científico

Centro Nacional de Biotecnología

SPAIN

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Esther Tamayo

University of the Basque Country

SPAIN

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Soraia Melo

Recipient of a Postdoctoral research fellowship funded by the American association “No Stomach for Cancer” as part of the project: “Nuclear biomarkers for predictive prognosis of hereditary diffuse gastric cancer", headed by Raquel Seruca, MD, PhD.

Instituto de Investigação e Inovação em Saúde da Universidade do Porto

PORTUGAL

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Yongsoo Kim

Assistant professor

Amsterdam University Medical Centers

NETHERLANDS

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Paul Hofman

Université Côte d'Azur

FRANCE

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Marius Ilié

Professor, PU-PH

Centre Hospitalier Universitaire de Nice

FRANCE

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Luka Brcic

Medical University of Graz

AUSTRIA

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Joana Almeida-Tavares

Assistant professor

Universidade Nova de Lisboa

PORTUGAL

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Iñaki Comas

Full Profesor

Consejo Superior de Investigaciones Cientificas

SPAIN

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Perminder Phull

University of Aberdeen

UNITED KINGDOM

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Anthonie van der Wekken

Scientific Staff

University of Groningen

NETHERLANDS

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Luis Bujanda

University of the Basque Country/Euskal Herriko Unibertsitatea (UPV/EHU)

SPAIN

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Helena F Florindo

Associate Professor with habilitation

Faculty of Pharmacy, University of Lisbon

PORTUGAL

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Dieter Saur

Technical University of Munich

GERMANY

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Manuel António Rodrigues Teixeira

Guest Full Professor

Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar

PORTUGAL

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Filipa Vale

Universidade de Lisboa Faculdade de Farmácia

PORTUGAL

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Kengo Tokunaga

Professor

School of Medicine, Kyorin University

JAPAN

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Ana Isabel Neves de Matos

PhD student (PhD research grant) at Research Institute for Medicines (iMed.ULisboa), Faculdade de Farmácia and Instituto Superior Técnico, Universidade de Lisboa, Lisboa, Portugal. FCT / AIM – Avanced integrated Microsystems Doctoral Program (IST) funded PhD research grant entitled “COMBI-CRC: combinatorial multivalent nanoplatform for colorectal cancer treatment”; reference PD/BD/113959/2015 (supervisor: Prof. Helena Fialho Florindo (iMed.ULisboa); co-supervisor: Prof. João Pedro Conde (IST)

Universidade de Lisboa Instituto Superior Técnico

PORTUGAL

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Bauke Ylstra

Director Tumor Genome Analysis Core

Amsterdam University Medical Centers

NETHERLANDS

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Vicente Martín-Sánchez

JEFE DE GRUPO

Universidad de León

SPAIN

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Paula Borralho Nunes

Senior Pathologist

PORTUGAL

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SONIA MELO

Affiliate Professor

PORTUGAL

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Álvaro Chiner-Oms

Researcher

Fisabio

SPAIN

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Teodora Radonic

Amsterdam University Medical Centers

NETHERLANDS

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Eurico Manuel Januário Rodrigues Morais de Sá

Group Leader

Instituto de Investigação e Inovação em Saúde da Universidade do Porto

PORTUGAL

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Riziero Esposito Abate

Fondazione IRCCS Istituto Nazionale dei Tumori

ITALY

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Jose Carlos Machado

Research Interests

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Recent Grants

Articles (20)

Genomic determinants of antibiotic resistance for Helicobacter pylori treatment: a retrospective phenotypic and genotypic observational study

Dual mechanism of immune escape shapes the genetic and immunogenic landscape of mismatch repair-deficient colorectal tumours.

FGFR Testing in Metastatic Urothelial Carcinoma—Who, When, and How to Test

Performance and considerations in the use of diagnostic mutation panels for clonality testing in non-small-cell lung carcinoma

Off-The-Shelf Multivalent Nanoconjugate Cancer Vaccine Rescues Host Immune Response against Melanoma.

The Added Value of Genome-Wide Copy Numbers to Objectively Resolve Clonality of Multiple Tumors With Pulmonary Involvement and Ambiguous or Inconclusive Mutational Diagnosis.

A novel computational approach to dissect the cytoskeletal architecture of cancer cells with invasive potential

Exosomes define a local and systemic communication network in healthy pancreas and pancreatic ductal adenocarcinoma

Developments in predictive biomarker testing and targeted therapy in advanced stage non-small cell lung cancer and their application across European countries

Future perspective for the application of predictive biomarker testing in advanced stage non-small cell lung cancer

Gene content, phage cycle regulation model and prophage inactivation disclosed by prophage genomics in the Helicobacter pylori Genome Project

Effectiveness of Helicobacter pylori Treatments According to Antibiotic Resistance

E-cadherin variants associated with oral facial clefts trigger aberrant cell motility in a REG1A-dependent manner

Gastric Cancer Genetics and Its Implications for Diagnosis, Prognosis, and Treatment of the Disease

Corrigendum: Evaluation of PIK3CA mutations in advanced ER+/HER2-breast cancer in Portugal – U-PIK Project(Front. Mol. Biosci., (2023), 10, (1082915), 10.3389/fmolb.2023.1082915)

European Real-World Assessment of the Clinical Validity of a CE-IVD Panel for Ultra-Fast Next-Generation Sequencing in Solid Tumors

Evaluation of <i>PIK3CA</i> mutations in advanced ER+/HER2-breast cancer in Portugal - U-PIK Project.

Next-Generation Sequencing (NGS) in lung cancer care: Advantages, applications, and challenges

Next-Generation Sequencing of Breast Cancer in the Neoadjuvant Setting

A Machine Learning Approach for Predicting Microsatellite Instability using RNA-seq

Collaborators (27)

Óscar Núñez

Hector Peinado

Esther Tamayo

Soraia Melo

Yongsoo Kim

Paul Hofman

Marius Ilié

Luka Brcic

Joana Almeida-Tavares

Iñaki Comas

Perminder Phull

Anthonie van der Wekken

Luis Bujanda

Helena F Florindo

Dieter Saur

Manuel António Rodrigues Teixeira

Filipa Vale

Kengo Tokunaga

Ana Isabel Neves de Matos

Bauke Ylstra

Vicente Martín-Sánchez

Paula Borralho Nunes

SONIA MELO

Álvaro Chiner-Oms

Teodora Radonic

Eurico Manuel Januário Rodrigues Morais de Sá

Riziero Esposito Abate

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