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Manuel António Rodrigues Teixeira

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Director

Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar

Portugal

Research Interests

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Professors in Portugal Professors in Biostatistics Biostatistics professors in Portugal

About

Manuel António Rodrigues Teixeira is a Guest Full Professor at the Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar in Portugal. His research primarily focuses on epidemiological studies in oncology, genetic predisposition to cancers, and the molecular mechanisms of tumorigenesis. Recent articles include investigations into chronic myeloid leukaemia, familial nonmedullary thyroid carcinoma, and prostate cancer predisposition.

Recent Grants

Grant: Close

The Porto Comprehensive Cancer Center

Open Date: 2021-06-01

Close Date: 2023-11-30

Grant: Close

Health Research Network: From Lab to Community Health

Open Date: 2021-01-01

Close Date: 2025-12-31

Grant: Close

IPO Porto Research Center

Open Date: 2020-01-01

Close Date: 2023-12-31

Grant: Close

IPO Porto Research Center

Open Date: 2020-01-01

Close Date: 2023-12-31

Grant: Close

Portuguese Oncology Institute - Porto Research Center

Open Date: 2019-01-01

Close Date: 2019-12-31

Articles (36)

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Collaborators (77)

Montserrat Garcia-Closas

Professor of Epidemiology

Institute of Cancer Research

UNITED KINGDOM

Manuel António Rodrigues Teixeira

Research Interests

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About

Recent Grants

Articles (36)

Polygenic risk score with KLK3 SNP-SNP interaction pairs for predicting prostate cancer aggressiveness.

FGFR Testing in Metastatic Urothelial Carcinoma—Who, When, and How to Test

Targeted Prostate Cancer Screening in Carriers of BRCA1 or BRCA2 Pathogenic Germline Variants Detects Clinically Relevant Disease: 5-year Results from the IMPACT Study.

ATG16L1 and OPTN as a novel prognostic gene expression signature in acute myeloid leukemia survival

Clinical relevance of homologous recombination repair gene alterations in endometrial cancer patients in the era of molecular classification

Characterisation of a Portuguese origin founder missense variant in MSH6

Assessing clinical decision support system tools in precision oncology: piloting ring testing

Ovarian cancer in Portugal: a real-world evidence review

A Novel Deleterious Variant and a Founder Effect in Four New Families of <i>MBD4</i>-Associated Neoplasia Syndrome Recruited Over a Period of 20 Years

P-cadherin overexpression is associated with early transformation of the Fallopian tube epithelium and aggressiveness of tubo-ovarian high-grade serous carcinoma

Hereditary diffuse gastric cancer spectrum associated with germline CTNNA1 loss of function revealed by clinical and molecular data from 351 carrier families and over 37 000 non-carrier controls

Epidemiological characterization of chronic myeloid leukaemia patients at an oncologic centre: A retrospective observational study

Genome-wide association study of 398,238 women unveils seven loci associated with high-grade serous ovarian cancer.

Molecular characterisation of Mozambican patients diagnosed with colorectal adenocarcinoma

EGFR-STAT3 activation provides a therapeutic rationale for targeting aggressive ETV1-positive prostate cancer

Saliva-derived transcriptomic signature for gastric cancer detection using machine learning and leveraging publicly available datasets

The role of multi-organ cancer predisposition genes in the risk of inherited and histologically diverse gastric cancer

Identification of novel candidate predisposing genes in familial nonmedullary thyroid carcinoma implicating DNA damage repair pathways

Silver Nanoparticles (AgNPs) Uptake by Caveolae-Dependent Endocytosis is Responsible for Their Selective Effect Towards Castration Resistant Prostate Cancer

Cluster effect for SNP-SNP interaction pairs for predicting complex traits.

BUB1B monoallelic germline variants contribute to prostate cancer predisposition by triggering chromosomal instability

Multiple TP53 p.R337H haplotypes and implications for tumor susceptibility

The Initial Journey of Patients with Metastatic Pancreatic Cancer (PaCTO Project): A Nationwide Survey among Portuguese Specialist Physicians

Ovarian cancer pathology characteristics as predictors of variant pathogenicity in BRCA1 and BRCA2.

Genetic landscape of homologous recombination repair genes in early-onset/familial prostate cancer patients.

Evaluating approaches for constructing polygenic risk scores for prostate cancer in men of African and European ancestry.

PREDICT validity for prognosis of breast cancer patients with pathogenic BRCA1/2 variants.

Exome sequencing of affected duos and trios uncovers PRUNE2 as a novel prostate cancer predisposition gene

Evaluation of <i>PIK3CA</i> mutations in advanced ER+/HER2-breast cancer in Portugal - U-PIK Project.

Gastric Cancer: A Practical Review on Management of Individuals with Hereditary or Familial Risk for Gastric Cancer

Characterizing prostate cancer risk through multi-ancestry genome-wide discovery of 187 novel risk variants

Practical lessons learned from real-world implementation of the molecular classification for endometrial carcinoma

Combined germline and tumor mutation signature testing identifies new families with NTHL1 tumor syndrome

Genotype-first approach to identify associations between CDH1 germline variants and cancer phenotypes: a multicentre study by the European Reference Network on Genetic Tumour Risk Syndromes.

Copy number variants as modifiers of breast cancer risk for BRCA1/BRCA2 pathogenic variant carriers.

Cellular Aging Secretes: a Comparison of Bone-Marrow-Derived and Induced Mesenchymal Stem Cells and Their Secretome Over Long-Term Culture.

Collaborators (77)

Montserrat Garcia-Closas

Joseph Lachance

Chrystelle Colas

Louise Marquart

Johnny Lisboa

Carla Oliveira

Florence Menegaux

Adalgeir Arason

Frank Claessens

Belém Sampaio-Marques

Marco Montagna

Nora Pashayan

Hui-Yi Lin

Jacques Simard

Francisca Dias

FEI CHEN

António J. Salgado

Carolina Pires

Srdjan Novaković

Maria Jose Garcia

Maria José Bento

Sara Ricardo

Paul Townsend

Dylan Ferreira

Siddhartha Yadav

Inge Søkilde Pedersen

Diana M Eccles

Aswin George Abraham

Nadia Pinto

Diana Lousa

Cintia Fridman

Joana Almeida-Tavares

Denise G. O'Mahony

Ana L Teixeira

Thilo Dörk

Karina Dalsgaard Sørensen