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Jose Ordovas-Montanes

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Research Faculty

Boston Children's Hospital

United States

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Grant: Open

Mapping host responses in the nasal mucosa during respiratory viral infections to identify cellular determinants of severe disease

Open Date: 2026-08-01

Close Date: 2033-07-31

Articles (15)

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Collaborators (11)

Michael Robben

Assistant Professor

University of Illinois Urbana–Champaign

UNITED STATES

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Semir Beyaz

Principal Investigator

Cold Spring Harbor Laboratory

UNITED STATES

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Lori Coburn

Associate Professor

Vanderbilt University Medical Center

UNITED STATES

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Michelle Galeas-Pena

Assistant Professor

Tulane University

UNITED STATES

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Alison Simmons

Director

University of Oxford

UNITED KINGDOM

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Jaclyn Walsh

Staff Scientist

Boston Children's Hospital

UNITED STATES

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Ulrich von Andrian

Professor

Harvard Medical School

UNITED STATES

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Colin Bingle

Professor

University of Sheffield

UNITED KINGDOM

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Zhongyang Wu

Professor

University of Science and Technology of China

CHINA

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Alex K. Shalek

Associate Professor

Massachusetts Institute of Technology

UNITED STATES

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Krishnan Raghunathan

Senior Scientist

Boston Children's Hospital

UNITED STATES

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Jose Ordovas-Montanes

Research Interests

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Recent Grants

Articles (15)

Nasal immunity in respiratory viral infection, transmission, and protection

Single-cell RNA-seq reveals disease-specific CD8+ T cell clonal expansion and a high frequency of transcriptionally distinct double-negative T cells in diabetic NOD mice

A niche-dependent redox rheostat regulates epithelial stem cell fate.

Toward precision medicine: Inflammatory nasal epithelial transcriptomic profiles in long COVID.

Enhanced Production of Lipid Mediators in Plasma and Activation of DNA Damage Pathways in PBMCs Are Correlated With the Severity of Ancestral SARS-CoV-2 Infection.

Variants and vaccines impact nasal immunity over three waves of SARS-CoV-2.

An enhanced IL17 and muted type I interferon nasal epithelial cell state characterizes severe COVID-19 with fungal coinfection

Primary nasal influenza infection rewires tissue-scale memory response dynamics

Distinct olfactory mucosal macrophage populations mediate neuronal maintenance and pathogen defense

Type III interferons induce pyroptosis in gut epithelial cells and impair mucosal repair.

Deconstructing inflammatory memory across tissue set points using cell circuit motifs.

The choroid plexus synergizes with immune cells during neuroinflammation.

Respiratory epithelial cell types, states and fates in the era of single-cell RNA-sequencing

A Roadmap for the Human Gut Cell Atlas

Leveraging polygenic enrichments of gene features to predict genes underlying complex traits and diseases.

Collaborators (11)

Michael Robben

Semir Beyaz

Lori Coburn

Michelle Galeas-Pena

Alison Simmons

Jaclyn Walsh

Ulrich von Andrian

Colin Bingle

Zhongyang Wu

Alex K. Shalek

Krishnan Raghunathan

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