Joseph Lorent

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Assistant Professor

UCLouvain

Belgium

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About

Joseph Lorent is an Assistant Professor at UClouvain in Belgium. His research primarily focuses on cell membrane dynamics, lipid asymmetry, and the interactions between immune cells and membranes. Recent publications highlight his work on the phospholipid imbalance in cell membranes, membranolytic mechanisms involving oxidized phospholipids, and the biophysical properties of bacterial membranes.

Recent Grants

Grant: Close

Molecular pharmacology and biophysics applied to drug-target interactions

Open Date: 2022-10-01

Close Date: 2024-10-01

Grant: Close

Bourse du patrimoine

Open Date: 2012-09-01

Close Date: 2013-02-01

Articles (20)

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2020

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2020

Collaborators (12)

Xue Bao

Utrecht University

NETHERLANDS

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Kandice Levental

Associate Professor, Research-track

University of Virginia

UNITED STATES

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Stephen Cochrane

Lecturer in Organic Chemistry

The Queen's University Belfast

UNITED KINGDOM

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Milka Doktorova

University of Virginia

UNITED STATES

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Anton de Kroon

Associate professor

Utrecht University

NETHERLANDS

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Maik Derks

Eindhoven University of Technology

NETHERLANDS

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Rhythm Shukla

Utrecht University

NETHERLANDS

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Andreas Sonnen

European Bioinformatics Institute

UNITED KINGDOM

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Ishwar Singh

Reader

University of Liverpool

UNITED KINGDOM

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Ana Sobota

Eindhoven University of Technology

NETHERLANDS

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Michal Surma

Head of the Laboratory

POLAND

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Markus Weingarth

NETHERLANDS

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Joseph Lorent

Research Interests

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About

Recent Grants

Articles (20)

Immune cell activation produces locally scrambled foci of plasma membrane lipids

Cell membranes sustain phospholipid imbalance via cholesterol asymmetry.

Structure and pH Dependence of Membranolytic Mechanisms by Truncated Oxidized Phospholipids

Measuring plasma membrane fluidity using confocal microscopy.

Asymmetric membrane properties through a protein lens

Asymmetric membrane properties through a protein lens

Synergistic effects of oxidative and acid stress on bacterial membranes of Escherichia coli and Staphylococcus simulans

Host defence peptide plectasin targets bacterial cell wall precursor lipid II by a calcium-sensitive supramolecular mechanism

Immune cell activation produces locally scrambled foci of plasma membrane lipids

Insight into the outer membrane asymmetry of P. aeruginosa and the role of MlaA in modulating the lipidic composition, mechanical, biophysical, and functional membrane properties of the cell envelope

Lipid scrambling facilitates membrane vesiculation through decreasing membrane stiffness

Teixobactin kills bacteria by a two-pronged attack on the cell envelope.

Metabolic labeling of the bacterial peptidoglycan by functionalized glucosamine

Multifaceted Activities of Seven Nanobodies against Complement C4b

Shortening of membrane lipid acyl chains compensates for phosphatidylcholine deficiency in choline‐auxotroph yeast

Lipid Membranes as Key Targets for the Pharmacological Actions of Ginsenosides

Structural Modifications Controlling Membrane Raft Partitioning and Curvature in Human and Viral Proteins

Mode of action of teixobactins in cellular membranes

Plasma membranes are asymmetric in lipid unsaturation, packing and protein shape

Myelin-Associated MAL and PLP Are Unusual Among Multi-Pass Transmembrane Proteins in Preferring Ordered Membrane Domains

Collaborators (12)

Xue Bao

Kandice Levental

Stephen Cochrane

Milka Doktorova

Anton de Kroon

Maik Derks

Rhythm Shukla

Andreas Sonnen

Ishwar Singh

Ana Sobota

Michal Surma

Markus Weingarth

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