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Joseph Shaw

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Associate Scientist, Clinical Epidemiology Program

Ottawa Hospital Research Institute

Canada

Research Interests

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Recent Grants

Grant: Open

Active Cancer Patients Having Cancer Related Invasive Procedures or Surgery and Needing Perioperative Management of Anticoagulation Therapy (ACE-HIGH) - A Prospective Management Cohort Study

Open Date: 2025-04-01

Close Date: 2030-03-01

Grant: Close

Peri-procedural management of direct oral anticoagulants for central venous catheters in cancer patients with venous thromboembolism or atrial fibrillation (VENO CAT)

Open Date: 2025-04-01

Close Date: 2026-04-01

Grant: Open

Advancing Precision in Prediction of Anticoagulant-Associated Bleeding Risks in Racialized Minority Populations

Open Date: 2025-03-01

Close Date: 2028-03-01

Grant: Open

Thrombin generation assay to improve risk prediction of reperfusion outcomes in acute ischemic stroke

Open Date: 2025-01-01

Close Date: 2027-03-01

Grant: Open

Perioperative Anticoagulant Use for Surgery Evaluation Study Part 2 Randomized Controlled Trial

Open Date: 2024-04-01

Close Date: 2027-03-01

Articles (20)

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Collaborators (18)

Kari Tikkinen

University of Helsinki

FINLAND

Joseph Shaw

Research Interests

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Recent Grants

Articles (20)

Surgical and procedural bleed risk stratification for anticoagulated patients undergoing planned surgery: guidance from the ISTH SSC Subcommittee on Perioperative and Critical Care Thrombosis and Hemostasis

Thrombin generation and the pharmacodynamics of oral anticoagulants

Ischemic Limb Necrosis and Symmetrical Peripheral Gangrene During Vasopressor Support in Severe Shock States: Thromboinflammatory Microvascular Injury as the Pathogenic Mechanism

Anaphylaxis and coagulopathy: from rare case reports to mechanistic insights

Effect of PCC on thrombin generation in patients on FXaI with bleeding or needing urgent surgery (GAUGE)

A light in the dark—reframing direct oral anticoagulant pharmacokinetics and pharmacodynamics for near-patient decision-making

Use of factor concentrates for the management of perioperative bleeding: guidance from the ISTH SSC Subcommittee on Perioperative and Critical Care Thrombosis and Hemostasis

Targeted anticoagulant reversal, unintended consequences: lessons from andexanet alfa

Thrombin generation and the pharmacodynamics of parenteral anticoagulants

“Perioperative use of factor concentrates and blood products: a survey of clinical practices in the United States: Communication from the ISTH Subcommittee on Perioperative and Critical Care”: reply

Anticoagulation Reversal and the Risk of Arterial Thrombosis - A Double-Edged Sword

Perioperative use of factor concentrates and blood products—a survey of clinical practices in the United States: communication from the ISTH Subcommittee on Perioperative and Critical Care

Emergent cardiac surgery, andexanet alfa–induced heparin resistance, and prothrombotic effects: coagulation chaos?

Reversal of direct oral anticoagulants: guidance from the SSC of the ISTH: reply

Impact of limited language proficiency on participation in venous thromboembolism research: a retrospective analysis

Thrombosis, Translational Medicine, and Biomarker Research: Moving the Needle

Influence of Direct Oral Anticoagulant Levels and Thrombin Generation on Postoperative Bleeding [SONAR]: A Nested Case–Control Study

Direct oral anticoagulant (DOAC) levels, bleeding, and breakthrough thrombosis: fog of war

Reversal of direct oral anticoagulants: guidance from the SSC of the ISTH

Prothrombin complex concentrate for direct factor Xa inhibitor-associated bleeding or before urgent surgery

Collaborators (18)

Kari Tikkinen

Deborah Siegal

Marc Carrier

Hugo ten Cate

Jameel Abdulrehman

Bianca Rocca

KIMBERLEY YOUKHANA

Jeffrey Weitz

Edsel B. Ing

Aurélien Delluc

Maria P Ntalouka

Dylan Burger

Grégoire Le Gal

Jerrold Levy

Cheryl Maier

Guillaume Martel

Yan Xu

Kenichi Tanaka

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