Josie Parker

Lecturer in Biochemistry

Cardiff University

United Kingdom

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Josie Parker is a Lecturer in Biochemistry at Cardiff University, UK. Her research focuses on antifungal resistance mechanisms in various fungal pathogens, including Candida species and Aspergillus. Recent publications examine topics such as antifungal susceptibility testing, genetic interactions affecting drug resistance, and the molecular characterization of ergosterol biosynthesis pathways.

Articles (17)

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2025

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2021

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2020

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2020

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2020

Collaborators (9)

Claire Price

UNITED KINGDOM

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Adela Martin-Vicente

University of Tennessee Health Science Center

UNITED STATES

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Joseph Heitman

Duke University Medical Center

UNITED STATES

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Glen E. Palmer

UNITED STATES

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Scott Moye-Rowley

Professor

Iowa State University

UNITED STATES

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Gary P. Moran

IRELAND

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Suhail Ahmad

KUWAIT

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Rachael Moses

University of Melbourne

AUSTRALIA

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Steven Kelly

Professor

Swansea University

UNITED KINGDOM

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Josie Parker

Research Interests

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Articles (17)

Head-to-Head Comparison of Etest, MICRONAUT-AM EUCAST and Reference Broth Microdilution-Based CLSI Results for Candida kefyr Antifungal Susceptibility Testing: Implications for Detection of Reduced Susceptibility to Amphotericin B

Genetic interaction analysis of <i>Candida glabrata</i> transcription factors <i>CST6</i> and <i>UPC2A</i> in the regulation of respiration and fluconazole susceptibility

Exploring medium and long arm extensions of 1,2,4-triazole derivatives as <i>Candida albicans</i> 14α-demethylase (CYP51) inhibitors

Alternative ergosterol biosynthetic pathways confer antifungal drug resistance in the human pathogens within the Mucor species complex

The sterol C-24 methyltransferase encoding gene, erg6, is essential for viability of Aspergillus species

A secondary mechanism of action for triazole antifungals in Aspergillus fumigatus mediated by hmg1

Deletion of the Candida albicans TLO gene family results in alterations in membrane sterol composition and fluconazole tolerance.

Molecular Characterization and Sterol Profiles Identify Nonsynonymous Mutations in <i>ERG2</i> as a Major Mechanism Conferring Reduced Susceptibility to Amphotericin B in Candida kefyr

Titration of C-5 Sterol Desaturase Activity Reveals Its Relationship to Candida albicans Virulence and Antifungal Susceptibility Is Dependent upon Host Immune Status

Cytochrome P450 168A1 from Pseudomonas aeruginosa is involved in the hydroxylation of biologically relevant fatty acids

Loss-of-Function ROX1 Mutations Suppress the Fluconazole Susceptibility of upc2A Δ Mutation in Candida glabrata, Implicating Additional Positive Regulators of Ergosterol Biosynthesis

In vivo emergence of high-level resistance during treatment reveals the first identified mechanism of amphotericin B resistance in Candida auris

Species-Specific Differences in C-5 Sterol Desaturase Function Influence the Outcome of Azole Antifungal Exposure

Insights in the molecular mechanisms of an azole stress adapted laboratory-generated Aspergillus fumigatus strain

Small‐Molecule Inhibitors Targeting Sterol 14α‐Demethylase (CYP51): Synthesis, Molecular Modelling and Evaluation AgainstCandida albicans

Mutations in TAC1B : a Novel Genetic Determinant of Clinical Fluconazole Resistance in Candida auris

Controlled in vitro delivery of voriconazole and diclofenac to the cornea using contact lenses for the treatment of Acanthamoeba keratitis

Collaborators (9)

Claire Price

Adela Martin-Vicente

Joseph Heitman

Glen E. Palmer

Scott Moye-Rowley

Gary P. Moran

Suhail Ahmad

Rachael Moses

Steven Kelly

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