Scott Moye-Rowley

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Iowa State University

United States

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Scott Moye-Rowley is a Professor at the University of Iowa, United States. His research focuses on the molecular mechanisms of transcriptional regulation in fungal pathogens, particularly involving the Candida glabrata and Aspergillus fumigatus species. Recent publications include studies on regulatory pathways activated by antifungal drugs, as well as the functions of transcription factors and coactivators in gene expression.

Recent Grants

Grant: Close

Transcriptional networks governing A. fumigatus virulence

Open Date: 2021-09-22

Close Date: 2026-08-31

Grant: Close

Analysis of transcription factors determining azole resistance of Aspergillus fumigatus

Open Date: 2019-08-06

Close Date: 2024-07-31

Grant: Close

A new pathway for azole resistance in Aspergillus fumigatus

Open Date: 2015-06-15

Close Date: 2017-05-31

Grant: Close

Role of transcriptional regulation in Aspergillus fumigatus drug resistance

Open Date: 2011-06-01

Close Date: 2013-05-31

Grant: Close

Regulation of eukaryotic membrane structure and function

Open Date: 2007-02-01

Close Date: 2011-01-31

Articles (14)

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2024

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2024

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2024

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2023

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2023

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2023

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2022

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2022

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2022

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2022

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2022

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2021

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2021

Collaborators (3)

Josie Parker

Lecturer in Biochemistry

Cardiff University

UNITED KINGDOM

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Hubertus Haas Haas

Medical University of Innsbruck

AUSTRIA

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Mark Hall

Associate Professor

Purdue University

UNITED STATES

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Scott Moye-Rowley

Research Interests

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About

Recent Grants

Articles (14)

Overlapping coactivator function is required for transcriptional activation by the Candida glabrata Pdr1 transcription factor

Gene-specific transcriptional activation by the Aspergillus fumigatus AtrR factor requires a conserved C-terminal domain

Similarities and distinctions in the activation of the Candida glabrata Pdr1 regulatory pathway by azole and non-azole drugs

Rapid, efficient auxin-inducible protein degradation in Candida pathogens

Interactions between the transcription factors FfmA and AtrR are required to properly regulate gene expression in the fungus Aspergillus fumigatus

Regulation of High-Affinity Iron Acquisition, Including Acquisition Mediated by the Iron Permease FtrA, Is Coordinated by AtrR, SrbA, and SreA in Aspergillus fumigatus

Calcineurin is required for Candida glabrata Pdr1 transcriptional activation

Biochemical Identification of a Nuclear Coactivator Protein Required for AtrR-Dependent Gene Regulation in Aspergillus fumigatus

Nonidentical function of Upc2A binding sites in the Candida glabrata CDR1 promoter

Differential Functions of Individual Transcription Factor Binding Sites in the Tandem Repeats Found in Clinically Relevant cyp51A Promoters in Aspergillus fumigatus

Azole-Resistant Alleles of ERG11 in Candida glabrata Trigger Activation of the Pdr1 and Upc2A Transcription Factors

Aspergillus fumigatus ffmA Encodes a C 2 H 2 -Containing Transcriptional Regulator That Modulates Azole Resistance and Is Required for Normal Growth

Loss-of-Function ROX1 Mutations Suppress the Fluconazole Susceptibility of upc2A Δ Mutation in Candida glabrata, Implicating Additional Positive Regulators of Ergosterol Biosynthesis

The Candida glabrata Upc2A transcription factor is a global regulator of antifungal drug resistance pathways

Collaborators (3)

Josie Parker

Hubertus Haas Haas

Mark Hall

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