Jürgen Götz

The Queensland Brain Institute at The University of Queensland is offering a postdoctoral research opportunity in neuroscience focused on therapies for Alzheimer’s disease. The project sits at the intersection of low-intensity ultrasound, antibody engineering, and neurodegeneration, with a strong emphasis on improving anti-tau monoclonal antibodies so they can more effectively reach intraneuronal targets in the brain. In this research-focused role, the fellow will work on optimizing a modified monoclonal antibody for increased intracellular uptake in vivo and on improving its specificity for neuronal uptake using innovative approaches. The role includes designing and carrying out in vitro and in vivo studies to validate tau-targeting antibodies, analysing data, preparing manuscripts and reports, and presenting findings in academic settings. The work is embedded in a collaborative and high-performing neuroscience team within a vibrant research community dedicated to discovery and translation. The post offers the chance to contribute to a program aimed at developing novel therapeutic outcomes for Alzheimer’s disease, with direct involvement in antibody development and translational neuroscience research. The environment is research-intensive, interdisciplinary, and closely connected to the broader institute and university research community.