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Jun Feng

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Professor with Tenure

University of South Florida

United States

Research Interests

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About

Dr. Jun Feng is an Associate Professor of Surgery at Brown University Warren Alpert Medical School in the United States. His research primarily focuses on microvascular dysfunction and contractile responses in patients undergoing cardiac surgery, as well as the effects of diabetes and hypertension on cardiovascular health. He has published extensively on topics including cerebral microvascular reactivity, coronary microvascular response, and the role of chronic hypertension in neurocognitive decline after cardiac surgery.

Recent Grants

Grant: Close

CaMKII and Endothelial SK Channel Function in Diabetic Coronary Microcirculation

Open Date: 2023-09-01

Close Date: 2025-08-01

Grant: Close

SARS-COV-2 Spike protein and pulmonary endothelial function

Open Date: 2021-01-01

Close Date: 2022-01-01

Grant: Close

Metabolic Modulation of SK/IK Channels for Cerebrovascular Endothelial Protection Related to Alzheimer's Disease

Open Date: 2020-09-01

Close Date: 2023-03-01

Grant: Close

Department Research Retention Fund

Open Date: 2019-01-01

Close Date:

Grant: Close

Division Research Retention Fund

Open Date: 2019-01-01

Close Date:

Articles (28)

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2021

Collaborators (11)

Tae Yun Kim

Research Professor

Korea University

SOUTH KOREA

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Lucian Lozonschi

TGH Endowed Chair, Professor with tenure and Chief

University of South Florida

UNITED STATES

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Frank W. Sellke

Chief of Cardiothoracic Surgery

Rhode Island Hospital

UNITED STATES

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William Jackson

Professor

Michigan State University

UNITED STATES

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Suzanne M de la Monte

UNITED STATES

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Afshin Ehsan

Chief of Cardiovascular and Thoracic Surgery

Baylor University Medical Center

UNITED STATES

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Jun Feng

Research Interests

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About

Recent Grants

Articles (28)

Semaglutide augments vascular proliferation and cardiac performance in a large animal model of ischemic cardiomyopathy

Senolytic reduction of senescent cells mitigates atrial arrhythmia vulnerability in aging rabbits.

Serotonin Signaling and Vascular Reactivity in Cardiometabolic Disease and Cardiac Surgery

Linagliptin enhances coronary microvascular function and collateralization in a large animal model of cardiometabolic syndrome.

Endothelin-1 and Vasomotor Tone Following Cardioplegic Ischemia/Reperfusion and Cardiopulmonary Bypass.

Cellular and Molecular Mechanisms of SARS-CoV-2 Spike Protein-Induced Endothelial Dysfunction

Impaired contractile response of human peripheral arterioles to angiotensin II after cardiopulmonary bypass.

Age-specific Increase in vasopressin-induced Coronary Microvascular Contractile Response in Patients Undergoing Cardiac Surgery.

Microvascular Dysfunction Following Cardioplegic Arrest and Cardiopulmonary Bypass: Impacts of Diabetes and Hypertension.

Impaired cerebral microvascular reactivity and endothelial SK channel activity in a streptozotocin-treated mouse model of Alzheimer's disease

Female patients exhibit altered vasopressin-induced coronary microvascular contractile response and molecular signaling following cardiac surgery

The Role of Preoperative Chronic Hypertension in Neurocognitive Decline after Cardiac Surgery: A Retrospective Cohort Study

Uncontrolled hypertension contributes to vascular permeability after cardioplegic arrest and cardiopulmonary bypass.

Protein Kinase C-β Inhibition and Survival Signaling after Simulated Cardioplegic-Ischemia/Reperfusion in Nondiabetic and Diabetic Human Coronary Arterial Endothelial Cells.

Role of Protein Kinase C in Metabolic Regulation of Coronary Endothelial Small Conductance Calcium‐Activated Potassium Channels

Role of Protein Kinase C in Metabolic Regulation of Coronary Endothelial Small Conductance Calcium‐Activated Potassium Channels

Crafting a Rigorous, Clinically Relevant Large Animal Model of Chronic Myocardial Ischemia: What Have We Learned in 20 Years?

Increased Coronary Contraction to Thromboxane A2 in Cardiac Surgery Patients With Poorly Controlled Hypertension

Microvascular dysfunction following cardiopulmonary bypass plays a central role in postoperative organ dysfunction.

Poorly controlled hypertension is associated with increased coronary myogenic tone in patients undergoing cardiac surgery with cardiopulmonary bypass

Pulmonary hypertension associated with cardiopulmonary bypass and cardiac surgery.

From Plasma Free Hemoglobin To Exosome Hemoglobin

Mechanisms and clinical implications of endothelium-dependent vasomotor dysfunction in coronary microvasculature.

Metabolic regulation and dysregulation of endothelial small conductance calcium activated potassium channels.

Glycemic control is not associated with neurocognitive decline after cardiac surgery.

The cardiac molecular setting of metabolic syndrome in pigs reveals disease susceptibility and suggests mechanisms that exacerbate COVID-19 outcomes in patients.

Inhibition of mitochondrial reactive oxygen species improves coronary endothelial function after cardioplegic hypoxia/reoxygenation.

Chronic Inhibition of mROS Protects Against Coronary Endothelial Dysfunction in Mice With Diabetes.

Collaborators (11)

Tae Yun Kim

Lucian Lozonschi

Frank W. Sellke

William Jackson

Suzanne M de la Monte

Afshin Ehsan

Nicholas Sellke

Nilufer N Turan

Ruhul Abid

David R Van Wagoner

Meghamsh Kanuparthy

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