Jus St. John

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Professor

University of Adelaide

Australia

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About

Professor Jus St. John is a faculty member at The University of Adelaide, Australia. His research focuses on mitochondrial DNA dynamics, particularly the effects of mtDNA supplementation in oocytes and its implications for developmental biology. Recent publications explore topics such as oocyte quality, cell cycle regulation in porcine blastocysts, and the relationship between dietary changes and gene expression in Drosophila larvae.

Recent Grants

Grant: Close

UNDERSTANDING THE BENEFITS AND LIMITATIONS OF METAPHASE II SPINDLE TRANSFER

Open Date: 2021-01-01

Close Date: 2025-12-31

Grant: Close

Understanding how mitochondrial DNA contributes to embryo development.

Open Date: 2019-01-01

Close Date:

Grant: Close

Improving oocyte mitochondrial DNA copy number to enhance female reproductive capacity.

Open Date: 2018-01-01

Close Date: 2020-12-31

Grant: Close

Diet influences the selective advantage of mitochondrial DNA mutations

Open Date: 2016-01-01

Close Date: 2020-08-31

Grant: Close

Metabolic and molecular basis of embryo signalling

Open Date: 2015-01-01

Close Date: 2018-12-31

Articles (13)

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2025

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2024

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2024

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2023

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2023

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2023

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2022

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2022

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2022

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2022

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2021

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2021

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2020

Collaborators (1)

Margaret Morris

Professor of Pharmacology, Head

UNSW Sydney

AUSTRALIA

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Jus St. John

Research Interests

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Contact this professor

About

Recent Grants

Articles (13)

Can the Supplementation of Oocytes with Extra Copies of mtDNA Impact Development Without Being Transmitted? A Molecular Account

Supplementation of Oocytes by Microinjection with Extra Copies of mtDNA Alters Metabolite Profiles and Interactions with Expressed Genes in a Tissue-Specific Manner

Nuclear transfer leads to aberrant cell cycle regulation and translation, as determined by gene expression, and selection of mitochondrial DNA in porcine blastocysts

Mitochondrial DNA Supplementation of Oocytes Has Downstream Effects on the Transcriptional Profiles of Sus scrofa Adult Tissues with High mtDNA Copy Number

Mitochondrial DNA Deficiency and Supplementation in Sus scrofa Oocytes Influence Transcriptome Profiles in Oocytes and Blastocysts

Does supplementation of oocytes with additional mtDNA influence developmental outcome?

Ancestral dietary change alters the development of Drosophila larvae through MAPK signalling

Mitochondrial supplementation of Sus scrofa metaphase II oocytes alters DNA methylation and gene expression profiles of blastocysts

The role of mtDNA in oocyte quality and embryo development.

Low guanine content and biased nucleotide distribution in vertebrate mtDNA can cause overestimation of non-CpG methylation

Epigenetic Regulation of the Nuclear and Mitochondrial Genomes: Involvement in Metabolism, Development, and Disease.

Analysis of Upstream Regulators, Networks, and Pathways Associated With the Expression Patterns of Polycystic Ovary Syndrome Candidate Genes During Fetal Ovary Development.

Lipopolysaccharide promotes Drp1‐dependent mitochondrial fission and associated inflammatory responses in macrophages

Collaborators (1)

Margaret Morris

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