Karam S. Aboudehen

University of Minnesota
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Articles (4)

Year:

2024

Year:

2023

This study identified scAAV/DJ as effective in transducing epithelial cells of the metanephric organ culture (MOC). We used scAAV/DJ shRNA to knockdown Pvt1 in cystic MOCs derived from Pkd1-null embryos. Downregulation of Pvt1 reduced cyst growth and decreased levels of c-MYC protein. These data suggest that suppression of Pvt1 activity in autosomal dominant polycystic kidney disease might reduce cyst growth.

Year:

2022

Year:

2020

Collaborators (3)

Vishal Patel

Associate Professor with Tenure

University of Texas Southwestern Medical Center

UNITED STATES
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Darren Wallace

Professor

University of Kansas Medical Center

UNITED STATES
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Peter Igarashi

Dean

Stony Brook University

UNITED STATES
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