Karam S. Aboudehen
University of Minnesota
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Articles (4)
Year:
2024
Year:
2023
This study identified scAAV/DJ as effective in transducing epithelial cells of the metanephric organ culture (MOC). We used scAAV/DJ shRNA to knockdown Pvt1 in cystic MOCs derived from Pkd1-null embryos. Downregulation of Pvt1 reduced cyst growth and decreased levels of c-MYC protein. These data suggest that suppression of Pvt1 activity in autosomal dominant polycystic kidney disease might reduce cyst growth.
Year:
2022
Year:
2020
Collaborators (3)
Vishal Patel
Associate Professor with Tenure
University of Texas Southwestern Medical Center
UNITED STATES
Darren Wallace
Professor
University of Kansas Medical Center
UNITED STATES
Peter Igarashi
Dean
Stony Brook University
UNITED STATES
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