Karin Pfisterer
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Reader in Tissue homeostasis, inflammation and immunity
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About
Karin Pfisterer is a Reader in Tissue Homeostasis, Inflammation, and Immunity at the Medical University of Vienna, Austria. Her research focuses on the extracellular matrix modifications in conditions such as psoriasis and atopic dermatitis, as well as the immune functions of skin cells and their role in inflammation. Recent publications include studies on the regulation of lysyl oxidase, the phageome in human skin, and the genetic factors contributing to familial melanoma.
Recent Grants
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Investigating the role of the extracellular matrix to induce “pioneer melanoma cells”
Open Date: 2021-01-01
Close Date: 2024-01-01
Grant: Close
FFG Career Grant
Open Date: 2019-01-01
Close Date: 2020-01-01
Grant: Close
Advanced Imaging Centre
Open Date: 2017-01-01
Close Date: 2018-01-01
Grant: Close
Human Dermal Mesenchymal Stem Cell Subsets Induce FoxP3 in Naive T cells
Open Date:
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Positions (1)
Karin Pfisterer
Medical University of Vienna
3 months ago
Postdoctoral Researcher in Melanoma and Extracellular Matrix Biology at the Medical University of Vienna (MedUni Vienna), Department of Dermatology. This is a full-time postdoctoral opening in the Pfisterer Lab, focused on melanoma, extracellular matrix (ECM) biology, tissue mechanics, cell-matrix interactions, and cancer progression. The project is part of PhotoMel , a Horizon Europe Mission Cancer consortium studying how UVA exposure and skincare additive interactions may influence melanoma risk and progression in young adults. The successful candidate will work in a multidisciplinary and collaborative environment with expertise spanning cancer biology, immunology, systems biology, tissue mechanics, advanced imaging, and computational biology. Research activities include characterizing ECM architecture and tissue mechanics in melanoma biopsies, studying melanoma invasion, developing workflows for melanoma cell subpopulation analysis, and investigating how ECM composition and mechanical properties regulate melanoma cell states and behavior. The role also involves advanced microscopy, including confocal, multiphoton, and second harmonic generation imaging, as well as quantitative image analysis, 3D tissue models, organotypic skin and dermis models, tumour spheroids, ex vivo human skin exposure assays, qPCR, transcriptomics, and CRISPR-Cas9-based perturbation studies. Eligibility highlights: PhD in Cell Biology, Cancer Biology, Molecular Biology, or a related field; experience in cell and molecular biology research; fluorescence microscopy and quantitative image analysis; strong communication skills; fluency in English; and the ability to work in an international consortium. Experience with 3D cell culture, organotypic models, ECM biology, mechanobiology, computational image processing, Python scripting, or CRISPR is desirable. Funding and terms: The position is full-time for 3.5 years, with employment under the collective agreement for university employees. The minimum gross annual salary is approximately €70,000, subject to adjustment based on prior experience. The project is EU-funded. Application deadline: 15 July 2026, 23:55 CET. How to apply: Send your application by email to [email protected]. Include a motivation letter, CV, transcripts or PhD thesis draft if applicable, evidence of research productivity, and contact details for two academic referees. Further information is available on the MedUni Vienna researcher page.
3 months ago
Articles (12)
Year:
2025
Year:
2023
Dysbiosis of skin microbiota drives the progression of atopic dermatitis (AD). The contribution of bacteriophages to bacterial community compositions in normal and inflamed skin is unknown. Using shotgun metagenomics from skin swabs of healthy individuals and patients with AD, we found 13,586 potential viral contiguous DNA sequences, which could be combined into 164 putative viral genomes including 133 putative phages. The Shannon diversity index for the viral metagenome-assembled genomes (vMAGs) did not correlate with AD. In total, we identified 28 vMAGs that differed significantly between normal and AD skin. Quantitative polymerase chain reaction validation of three complete vMAGs revealed their independence from host bacterium abundance. Our data indicate that normal and inflamed skin harbor distinct phageomes and suggest a causative relationship between changing viral and bacterial communities as a driver of skin pathology.
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2023
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2023
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2022
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2022
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2022
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2021
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2021
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2021
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2020
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2020
Collaborators (11)
Simon Ameer-Beg
Professor of Optical Oncology
King's College London - Guy's Campus
Matthias Wielscher
Lecturer
Medical University of Vienna
Peter Steinberger
Medical University of Vienna
Judith Leitner
Medical University of Vienna
Michael Mildner
Assoc.-Prof. Priv.-Doz. Dr.
Medical University of Vienna
Huey-Jy Huang
Medical University of Vienna
Vladimir Leksa
Medical University of Vienna
Christine Radtke
-
Birgit Willinger
Medical University of Vienna
Adelheid Elbe-Bürger
Ao.Univ.Prof.Dr.
Medical University of Vienna
W. Weninger
Medical University of Vienna
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