Karolien De Bosscher

Full professor

Belgium

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Articles (10)

Year:

2023

Year:

2022

Year:

2022

Year:

2022

Year:

2022

Year:

2022

Year:

2022

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2022

Year:

2022

Year:

2021

Collaborators (4)

Ville Paakinaho

Assistant Professor (tenure track)

University of Eastern Finland

FINLAND

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Jorma Palvimo

Professor of Medical Biochemisty

University of Eastern Finland

FINLAND

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Tom Desmet

Prof.

Ghent University

BELGIUM

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Liza Dewyse

Vrije Universiteit Brussel

BELGIUM

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Karolien De Bosscher

Research Interests

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Articles (10)

The Biologist’s Guide to the Glucocorticoid Receptor’s Structure

Identification of mercaptoacetamide-based HDAC6 inhibitors <i>via</i> a lean inhibitor strategy: screening, synthesis, and biological evaluation

Reprogramming of glucocorticoid receptor function by hypoxia

Approaches towards tissue‐selective pharmacology of the mineralocorticoid receptor

Carboxylic acid bioisosteres in medicinal chemistry : synthesis and properties

Compound A attenuates proinflammatory cytokine-induced endoplasmic reticulum stress in beta cells and displays beneficial therapeutic effects in a mouse model of autoimmune diabetes

Hepatic glucocorticoid‐induced transcriptional regulation is androgen‐dependent after chronic but not acute glucocorticoid exposure

Novel assays monitoring direct glucocorticoid receptor protein activity exhibit high predictive power for ligand activity on endogenous gene targets

Point mutation I634A in the glucocorticoid receptor causes embryonic lethality by reduced ligand binding

Combined glucocorticoid resistance and hyperlactatemia contributes to lethal shock in sepsis

Collaborators (4)

Ville Paakinaho

Jorma Palvimo

Tom Desmet

Liza Dewyse

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