Ken Bracke

Associate Professor

Ghent University

Belgium

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About

Ken Bracke is an Associate Professor at Ghent University in Belgium. His research primarily focuses on chronic obstructive pulmonary disease (COPD), asthma, and lung microbiota, with recent articles exploring the regulation of inflammatory responses and the role of various biomolecules in lung tissue remodeling. He is actively involved in investigating therapeutic strategies, including the use of nanogel inhalation therapy and RNA delivery systems.

Articles (25)

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2021

Collaborators (18)

Vamshikrishna Malyla

University of Sydney

AUSTRALIA

Ken Bracke

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Articles (25)

The Role of miR-320d in Regulation of Cigarette Smoke-Induced Pro-Inflammatory Responses in COPD

Vitronectin regulates lung tissue remodeling and emphysema in chronic obstructive pulmonary disease.

Pulmonary Microvascular Endothelial Cells Support Alveolar Epithelial Growth via Bone Morphogenetic Protein 6 Secretion

Altered levels of angiogenin and tRNA-derived fragments associate with severe asthma.

Selective Replacement of Cholesterol with Cationic Amphiphilic Drugs Enables the Design of Lipid Nanoparticles with Improved RNA Delivery

Evaluating β2-agonists as siRNA delivery adjuvants for pulmonary surfactant-coated nanogel inhalation therapy

Unraveling the Immune Profile in Emphysema Using Single-Cell and Imaging Mass Spectrometry

RIPK1 kinase-dependent inflammation and cell death contribute to the pathogenesis of COPD.

TLR7 promotes smoke-induced experimental lung damage through the activity of mast cell tryptase.

Blunted adaptive immune responses and acute exacerbations of COPD: breaking the code

Commensal bacteria of the lung microbiota synergistically inhibit inflammation in a three-dimensional epithelial cell model

Retrospective Study Shows That Serum Levels of Chemokine CXCL10 and Cytokine GDF15 Support a Diagnosis of Sporadic Inclusion Body Myositis and Immune-Mediated Necrotizing Myopathy

The arginine methyltransferase PRMT7 promotes extravasation of monocytes resulting in tissue injury in COPD.

An exploratory study of circulating cytokines and chemokines in patients with muscle disorders proposes CD40L and CCL5 represent general disease markers while CXCL10 differentiates between patients with an autoimmune myositis

Identification of asthma-associated microRNAs in bronchial biopsies

Reduced protection of RIPK3-deficient mice against influenza by matrix protein 2 ectodomain targeted active and passive vaccination strategies

Adverse roles of mast cell chymase-1 in COPD

Author Correction: Organ-specific genome diversity of replication-competent SARS-CoV-2 (Nature Communications, (2021), 12, 1, (6612), 10.1038/s41467-021-26884-7)

IL-10 producing regulatory B cells are decreased in blood from smokers and COPD patients

Epigenome-wide association study on diffusing capacity of the lung

A microRNA-21-mediated SATB1/S100A9/NF-κB axis promotes chronic obstructive pulmonary disease pathogenesis

Hippocampal Sclerosis in Frontotemporal Dementia: When Vascular Pathology Meets Neurodegeneration

MiR-223 is increased in lungs of patients with COPD and modulates cigarette smoke-induced pulmonary inflammation

Necroptosis signaling promotes inflammation, airway remodeling, and emphysema in chronic obstructive pulmonary disease

Organ-specific genome diversity of replication-competent SARS-CoV-2

Collaborators (18)

Vamshikrishna Malyla

Gang Liu

Fabio Luigi Massimo Ricciardolo

Emma Beckett

Alan Hsu

Wim Timens

Ine Lentacker

Tania Maes

Vigo Heissmeyer

Michael Schotsaert

Ahmed Edris

Guy Brusselle

Gaetano Caramori

Jos van Nijnatten

Koen Raemdonck

Richard Kim

Leandro Castellano

Jill Johnson

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