Ken-ichi Izutsu

Professor

International University of Health and Welfare

Japan

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Ken-ichi Izutsu is a Professor at the International University of Health and Welfare in Japan. His research primarily focuses on the characterization and application of dissolving microneedles, thermal analysis of aqueous solutions, and issues related to generic drug shortages and compliance in Japan. He has authored several recent articles that explore topics such as the mechanical properties of microneedles, dissolution profiles of pharmaceutical products, and innovative imaging techniques for drug delivery systems.

Ken-ichi Izutsu

Research Interests

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Articles (19)

Mechanical Characterization of Dissolving Microneedles: Factors Affecting Physical Strength of Needles

Analysis of Factors Related to Variation in Dissolution Profiles Estimated from Continuously Conducted Dissolution Tests of Generic Products

Effects of Apex Size on Dissolution Profiles in the USP II Paddle Apparatus

Fabrication and Characterization of Dissolving Microneedles for Transdermal Drug Delivery of Apomorphine Hydrochloride in Parkinson’s Disease

Application of the Thermal Analysis of Frozen Aqueous Solutions to Assess the Miscibility of Hyaluronic Acid and Polymers Used for Dissolving Microneedles

Generic Drug Shortage in Japan: GMP Noncompliance and Associated Quality Issues

Atomic Force Microscopic Imaging of mRNA-lipid Nanoparticles in Aqueous Medium

Folded, undulating, and fibrous doxorubicin sulfate crystals in liposomes

Real-time in situ X-ray micro-computed tomography study of the effect of impurities on the crystallization of amorphous nifedipine

Shortages of Prescription Drugs Due to Compliance and Quality Issues in Japan,医療用医薬品の品質問題と安定供給

Structural flexibility of apolipoprotein E-derived arginine-rich peptides improves their cell penetration capability

Simple bicarbonate buffer system for dissolution testing: Floating lid method and its application to colonic drug delivery system

In Vitro Sensitivity Analysis of the Gastrointestinal Dissolution Profile of Weakly Basic Drugs in the Stomach-to-Intestine Fluid Changing System: Explanation for Variable Plasma Exposure after Oral Administration

Discrimination of ranitidine hydrochloride crystals using X-ray micro-computed tomography for the evaluation of three-dimensional spatial distribution in solid dosage forms

Visualizing the spatial localization of ciclesonide and its metabolites in rat lungs after inhalation of 1-μm aerosol of ciclesonide by desorption electrospray ionization-time of flight mass spectrometry imaging

Approaches to supply bioequivalent oral solid pharmaceutical formulations through the lifecycles of products: Four-media dissolution monitoring program in Japan

Cold Flow Evaluation in Transdermal Drug Delivery Systems by Measuring the Width of the Oozed Adhesive

Contributions of the Japanese pharmacopoeia to the quality of generic pharmaceuticals

Detection of material-derived differences in the stiffness of egg yolk phosphatidylcholine-containing liposomes using atomic force microscopy

Collaborators (6)

Hiroyuki Yoshida

Hideyuki Sakoda

Daisuke Inoue

Toshihide Takagi

Yasuhiro Abe

Nahoko Uchiyama

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