Yasuhiro Abe

Section Chief

National Institute of Health Sciences

Japan

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About

Yasuhiro Abe is the Section Chief at the National Institute of Health Sciences in Japan. His research focuses on antibody engineering, the thermal analysis of biopolymers, and the role of immune cells in therapeutic applications. Recent articles highlight his work on CD30 antibodies, regulatory T cell expansion, and the dissolution profiles of various pharmaceutical products. He also investigates nitrosamine contamination in pharmaceuticals and employs advanced imaging techniques for nanoparticle analysis.

Articles (10)

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2025

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2024

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2024

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2024

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2024

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2024

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2024

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2024

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2023

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2023

Collaborators (4)

Hiroki Akiba

助教 / Assistant Professor

Kyoto University

JAPAN

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Hiroyuki Yoshida

National Institute of Health Sciences

JAPAN

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Ken-ichi Izutsu

Professor

International University of Health and Welfare

JAPAN

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Hidetomo Yokoo

National Institute of Health Sciences

JAPAN

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Yasuhiro Abe

Research Interests

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Articles (10)

Generation of antagonistic biparatopic anti-CD30 antibody from an agonistic antibody by precise epitope determination and utilization of structural characteristics of CD30 molecule

Analysis of Factors Related to Variation in Dissolution Profiles Estimated from Continuously Conducted Dissolution Tests of Generic Products

Effects of Apex Size on Dissolution Profiles in the USP II Paddle Apparatus

Nitrosamine contamination of pharmaceuticals: Cases in Japan, formation mechanisms, detection methods, regulatory perspectives, and insights

Application of the Thermal Analysis of Frozen Aqueous Solutions to Assess the Miscibility of Hyaluronic Acid and Polymers Used for Dissolving Microneedles

Effects of Glass Bead Size on Dissolution Profiles in Flow-through Dissolution Systems (USP 4)

An immunocytokine consisting of a TNFR2 agonist and TNFR2 scFv enhances the expansion of regulatory T cells through TNFR2 clustering

Correction: Effects of Apex Size on Dissolution Profiles in the USP II Paddle Apparatus (AAPS PharmSciTech, (2023), 25, 1, (9), 10.1208/s12249-023-02722-5)

Atomic Force Microscopic Imaging of mRNA-lipid Nanoparticles in Aqueous Medium

Bivalent structure of a TNFR2-selective and agonistic TNF-α mutein Fc-fusion protein enhances the expansion activity of regulatory T cells

Collaborators (4)

Hiroki Akiba

Hiroyuki Yoshida

Ken-ichi Izutsu

Hidetomo Yokoo

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