Kevin Rouault-Pierre

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Senior Lecturer

Barts Cancer Institute

United Kingdom

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About

Kevin Rouault-Pierre is a Senior Lecturer at Barts Cancer Institute in the UK. His research primarily focuses on myelodysplastic syndromes and acute myeloid leukemia, particularly the role of genomic mutations and therapeutic responses. Recent articles highlight his work on precision medicine, RNA missplicing, and the mechanisms of cell death in hematopoietic malignancies.

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Stress integration in haematopoietic cells

Open Date: 2017-09-01

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Articles (13)

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2025

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2024

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2024

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2023

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2023

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2023

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2023

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2022

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2022

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2022

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2022

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2021

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2021

Collaborators (20)

John G. Gribben

Queen Mary University of London

UNITED KINGDOM

Kevin Rouault-Pierre

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Recent Grants

Articles (13)

Low‐risk MDS—A spotlight on precision medicine for SF3B1‐mutated patients

The E592K variant of SF3B1 creates unique RNA missplicing and associates with high-risk MDS without ring sideroblasts

Pivotal role of the endoplasmic reticulum stress-related XBP1s/miR-22/SIRT1 axis in acute myeloid leukemia apoptosis and response to chemotherapy

CRISPR/dCas9 DNA methylation editing is heritable during human hematopoiesis and shapes immune progeny

Vitamin B5 and succinyl-CoA improve ineffective erythropoiesis in <i>SF3B1</i> -mutated myelodysplasia

Integrative phosphoproteomics defines two biologically distinct groups of KMT2A rearranged acute myeloid leukaemia with different drug response phenotypes

Mannose metabolism inhibition sensitizes acute myeloid leukaemia cells to therapy by driving ferroptotic cell death.

Targeting the lysine-specific demethylase 1 rewires kinase networks and primes leukemia cells for kinase inhibitor treatment

The transcription factor DDIT3 is a potential driver of dyserythropoiesis in myelodysplastic syndromes.

Germline ERCC excision repair 6 like 2 (ERCC6L2) mutations lead to impaired erythropoiesis and reshaping of the bone marrow microenvironment.

A dual role for the RNA helicase DHX34 in NMD and pre-mRNA splicing and its function in hematopoietic differentiation

Ectopic Humanized Mesenchymal Niche in Mice Enables Robust Engraftment of Myelodysplastic Stem Cells

Loss of tRNA-modifying enzyme Elp3 activates a p53-dependent antitumor checkpoint in hematopoiesis

Collaborators (20)

John G. Gribben

Henry Wood

Andrew Finch

William Dalton

Jude Fitzgibbon

Francesca Rapino

Louie van de Lagemaat

Pedro Madrigal

Pedro Rodriguez Cutillas

Javier F Cáceres

Christopher Bell

Ander Abarrategi

Céline Philippe

Eleni Maniati

Dasa Longman

Riley Bergman

Delphine Bernard

Juho Miettinen

G Vignir Helgason

Outi Kilpivaara

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