Konstantinos Stamatopoulos

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GlaxoSmithKline (United States)

United Kingdom

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Articles (10)

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2025

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2024

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2023

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2023

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2023

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2022

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2022

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2022

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2021

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2021

Collaborators (7)

Kostas Stamatopoulos

Visiting Professor

Karolinska Institutet

SWEDEN

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Caroline L. Hoad

UNITED KINGDOM

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Mark Simmons

University of Birmingham

UNITED KINGDOM

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Hannah Batchelor

University of Birmingham

UNITED KINGDOM

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Luca Marciani

Professor in Gastrointestinal Imaging

University of Nottingham

UNITED KINGDOM

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Kunal Taskar

Global Head PBPK Modeling

GSK

UNITED KINGDOM

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Nikoletta Fotaki

Professor at Department of Life Sciences

University of Bath

UNITED KINGDOM

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Konstantinos Stamatopoulos

Research Interests

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Articles (10)

Physiologically Based Pharmacokinetic Modeling of Phosphate Prodrugs─Case Studies: Fostemsavir and Fostamatinib

Development of a physiologically based pharmacokinetic model of fostemsavir and its pivotal application to support dosing in pregnancy

Use of In Vitro Dynamic Colon Model (DCM) to Inform a Physiologically Based Biopharmaceutic Model (PBBM) to Predict the In Vivo Performance of a Modified-Release Formulation of Theophylline

Physiologically Based Biopharmaceutics Model (PBBM) of Minimally Absorbed Locally Acting Drugs in the Gastrointestinal Tract—Case Study: Tenapanor

Integrating In Vitro Biopharmaceutics into Physiologically Based Biopharmaceutic Model (PBBM) to Predict Food Effect of BCS IV Zwitterionic Drug (GSK3640254)

Correction: Schütt et al. Simulating the Hydrodynamic Conditions of the Human Ascending Colon: A Digital Twin of the Dynamic Colon Model. Pharmaceutics 2022, 14, 184

Simulating the Hydrodynamic Conditions of the Human Ascending Colon: A Digital Twin of the Dynamic Colon Model

The Effect of Biorelevant Hydrodynamic Conditions on Drug Dissolution from Extended-Release Tablets in the Dynamic Colon Model

Luminal Fluid Motion Inside an In Vitro Dissolution Model of the Human Ascending Colon Assessed Using Magnetic Resonance Imaging

Modelling and Simulation of the Drug Release from a Solid Dosage Form in the Human Ascending Colon: The Influence of Different Motility Patterns and Fluid Viscosities.

Collaborators (7)

Kostas Stamatopoulos

Caroline L. Hoad

Mark Simmons

Hannah Batchelor

Luca Marciani

Kunal Taskar

Nikoletta Fotaki

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