Lana McClements

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University of Sydney

Australia

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Recent Grants

Grant: Close

Novel patient-specific in vitro 3D heart models for biomarker and target discovery in women at high-risk of heart disease

Open Date: 2020-03-01

Close Date: 2021-03-01

Grant: Close

GEMS Integrated Home Technology

Open Date: 2017-10-01

Close Date: 2018-03-01

Grant: Close

FKBPL, a novel and early biomarker of pre-eclampsia

Open Date: 2017-04-01

Close Date: 2018-10-01

Grant: Close

Novel placental tissue biomarkers and therapeutic targets association with pre-eclampsia

Open Date: 2017-02-01

Close Date: 2017-07-01

Articles (21)

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2023

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2023

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2023

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2023

Lecturer

University of Technology, Sydney

AUSTRALIA

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Bernard E. Tuch

AUSTRALIA

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Mark Ledwidge

Adjunct Professor

Trinity College Dublin

IRELAND

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Claire Rennie

University of Technology, Sydney

AUSTRALIA

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Hui Chen

Professor

University of Sydney

AUSTRALIA

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Carmine Gentile

University of Sydney

AUSTRALIA

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University of Sydney

AUSTRALIA

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Nicholas Matigian

Head of Bioinformatics & Principal Data Scientist

CIQUS

AUSTRALIA

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Xiaoxue (Helen) Xu

Lecturer

University of Sydney

AUSTRALIA

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Sahar Ghorbanpour

Lecturer (level B)

University of Sydney

AUSTRALIA

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Lana McClements

Research Interests

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Recent Grants

Articles (21)

The FKBPL-based therapeutic peptide, AD-01, protects the endothelium from hypoxia-induced damage by stabilising hypoxia inducible factor-α and inflammation.

Targeting oxidative stress in preeclampsia.

FK506 binding protein like, FKBPL, as a novel therapeutic target in 2D and 3D bioprinted, models of cardiac fibrosis

The role of sex differences in cardiovascular, metabolic, and immune functions in health and disease: a review for "Sex Differences in Health Awareness Day".

Maternal Immune Activation: Implications for Congenital Heart Defects.

Evaluating oxidative stress targeting treatments in in vitro models of placental stress relevant to preeclampsia.

Editorial: Adverse outcomes of preeclampsia: from mother to baby, pregnancy to postpartum.

Whole transcriptome profiling of placental pathobiology in SARS-CoV-2 pregnancies identifies placental dysfunction signatures.

3D in vitro modelling of post-partum cardiovascular health reveals unique characteristics and signatures following hypertensive disorders in pregnancy.

E-Cigarette Aerosol Condensate Leads to Impaired Coronary Endothelial Cell Health and Restricted Angiogenesis

A placenta-on-a-chip model to determine the regulation of FKBPL and galectin-3 in preeclampsia.

FK506-Binding Protein Like (FKBPL) Regulates Hypoxia-induced Factor-α and Restores Endothelial Function and Vascular Integrity in Ischaemia-induced Angiogenesis

Quantitative Point of Care Tests for Timely Diagnosis of Early‐Onset Preeclampsia with High Sensitivity and Specificity

Quantitative Point of Care Tests for Timely Diagnosis of Early‐Onset Preeclampsia with High Sensitivity and Specificity

The emerging importance of immunophilins in fibrosis development

Diagnostic and prognostic biomarkers reflective of cardiac remodelling in diabetes mellitus: A scoping review.

FK506-Binding Protein like (FKBPL) Has an Important Role in Heart Failure with Preserved Ejection Fraction Pathogenesis with Potential Diagnostic Utility.

New Treatment for Type 2 Diabetes Mellitus Using a Novel Bipyrazole Compound.

In vitro evaluation of a hybrid drug-delivery nanosystem for fibrosis prevention in cell therapy for Type 1 diabetes

Galectin-3 as a Prognostic Biomarker in Patients with First Acute Myocardial Infarction without Heart Failure.

PO6_24. Validation of FKBPL and CD44 as emerging biomarkers for early-onset preeclampsia diagnosis

Collaborators (19)

Charles Cranfield

Matthew Padula

Mark Colin Allenby

shihui wen

Amy Bottomley

Catherine Gorrie

Claire Richards

Bernard E. Tuch

Mark Ledwidge

Claire Rennie

Hui Chen

Carmine Gentile

Dayong Jin

Joan Röhl

Kristine McGrath

Louise Cole

Nicholas Matigian

Xiaoxue (Helen) Xu

Sahar Ghorbanpour

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