Laura Parkkinen

PhD Studentship in Translational Neuropathology at the University of Oxford , in the Nuffield Department of Clinical Neurosciences , with Laura Parkkinen’s lab. This project focuses on Parkinson’s disease and the molecular drivers of alpha-synuclein seeding and aggregation. The research aims to decipher the “aggregatome” surrounding alpha-synuclein aggregates, including proteins, post-translational modifications (PTMs), lipids, glycosaminoglycans, and other cofactors that may influence disease spread and progression. The work is part of the ASAP (Aligning Science Across Parkinson’s) Collaborative Research Network , involving the University of Oxford, the Max Planck Institute of Biochemistry, and LMU Munich. The team combines expertise in seed amplification assays , mass spectrometry-based proteomics , advanced biochemistry, neuropathology, and access to longitudinal patient cohorts with matched biosamples. Research materials include samples from the brain, cerebrospinal fluid, blood, skin, and stool , with the broader goal of improving understanding of disease progression and supporting better biomarkers and personalized therapies. The post highlights a world-class research environment, cutting-edge facilities, laboratory infrastructure, technical support, seminars, specialist meetings, and training opportunities at Oxford. Application deadline: noon Friday 23 October 2026. How to apply: Follow the application link in the post and consult the NDCN studentships and scholarships page for full instructions.