Päivi Pulkkila

University of Helsinki

Finland

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Articles (11)

Year:

2024

Year:

2024

Year:

2023

Year:

2023

Year:

2023

Year:

2023

Year:

2022

Year:

2022

Year:

2022

Year:

2021

Year:

2020

Collaborators (12)

Sven Sakson

University of Helsinki

FINLAND

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Mikko Airavaara

University of Helsinki

FINLAND

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Laura Parkkinen

Professor of Translational Neuropathology

University of Oxford

UNITED KINGDOM

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Michael Sendtner

Professor for Clinical Neurobiology

University of Würzburg

GERMANY

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Olesya Shpironok

University of Helsinki

FINLAND

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Maria Lindahl

University of Helsinki

FINLAND

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Michael D. Gershon

Professor

Columbia University

UNITED STATES

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Esa-Pekka Kumpula

University of Helsinki

FINLAND

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Liying Yu

University of Helsinki

FINLAND

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Juha Huiskonen

Professor of Structural Biology

University of Helsinki

FINLAND

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Sibylle Jablonka

Senior lecturer, group leader

University Hospital Würzburg

GERMANY

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Merja H Voutilainen

University of Helsinki

FINLAND

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Päivi Pulkkila

Research Interests

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Articles (11)

Unfolded protein response markers Grp78 and eIF2alpha are upregulated with increasing alpha‐synuclein levels in Lewy body disease

MANF protein expression is upregulated in immune cells in the ischemic human brain and systemic recombinant MANF delivery in rat ischemic stroke model demonstrates anti-inflammatory effects

MANF regulates neuronal survival and UPR through its ER-located receptor IRE1α

Aging disrupts MANF-mediated immune modulation during skeletal muscle regeneration

CDNF rescues motor neurons in models of amyotrophic lateral sclerosis by targeting endoplasmic reticulum stress

CDNF and MANF in the brain dopamine system and their potential as treatment for Parkinson's disease

CDNF Interacts with ER Chaperones and Requires UPR Sensors to Promote Neuronal Survival

Cerebral dopamine neurotrophic factor protects and repairs dopamine neurons by novel mechanism

CDNF and MANF regulate ER stress in a tissue-specific manner

The cytoprotective protein MANF promotes neuronal survival independently from its role as a GRP78 cofactor

Cerebral dopamine neurotrophic factor is essential for enteric neuronal development, maintenance, and regulation of gastrointestinal transit

Collaborators (12)

Sven Sakson

Mikko Airavaara

Laura Parkkinen

Michael Sendtner

Olesya Shpironok

Maria Lindahl

Michael D. Gershon

Esa-Pekka Kumpula

Liying Yu

Juha Huiskonen

Sibylle Jablonka

Merja H Voutilainen

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